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Pharmaceutical Chemistry Journal

, Volume 44, Issue 12, pp 702–704 | Cite as

Development of a chromatographic method for quantitative analysis of phenibut in biological samples

  • I. N. Tyurenkov
  • V. N. Perfilova
  • L. A. Smirnova
  • A. F. Ryabukha
  • E. A. Suchkov
  • S. A. Lebedeva
Article

An ion-pair chromatography method is developed using a reversed-phase C18 column with UV detection for the quantitative analysis of phenibut. The proposed method possesses sufficient selectivity and high sensitivity that enable its effective use during pharmacokinetic studies of phenibut in addition to other GABA derivatives in biological samples.

Key words

phenibut quantitative analysis HPLC 

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Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • I. N. Tyurenkov
    • 1
  • V. N. Perfilova
    • 2
  • L. A. Smirnova
    • 2
  • A. F. Ryabukha
    • 2
  • E. A. Suchkov
    • 2
  • S. A. Lebedeva
    • 2
  1. 1.Volgograd State Medical UniversityVolgogradRussia
  2. 2.Research Institute of PharmacologyVolgograd State UniversityVolgogradRussia

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