Pharmaceutical Chemistry Journal

, Volume 44, Issue 4, pp 199–201 | Cite as

Quantitative spectrophotometric determination of alkaloids in roots of Vinca herbacea

  • V. Yu. Vachnadze
  • E. Z. Dzhakeli
  • I. A. Dadeshidze
  • L. G. Kintsurashvili
Medical Plants
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A new spectrophotometric method has been developed for the quantitative determination of pharmacologically active alkaloids (maydine, reserpinine, kopsinine, tabersonine, norfluorocurarine) and their sum in roots of Vinca herbacea Walds. et Kit. The proposed technique is highly reproducible and adequately reflects the content of alkaloids in the roots and preparations of Vinca herbacea, which allows this method to be used for their standardization.

Key words

Vinca herbacea Walds. et Kit alkaloids spectrophotometry 

References

  1. 1.
    V. Yu. Vachnadze, M. M. Mudzhiri, E. Z. Dzhakeli, et al., Khim.-farm. Zh., 18(1), 67 – 71 (1984).Google Scholar
  2. 2.
    E. Z. Dzhakeli, I. S. Sikharulidze, M. M. Moistsrapishvili, and M. D. Gedevanishvili, in: Proceedings of the International Congress on Pharmaceuticals [in Russian], Tbilisi, Georgia (2002), p. 24.Google Scholar
  3. 3.
    V. Yu. Vachnadze, E. Z. Dzhakeli, M. M. Mudzhiri, et al., Exploratory Pharmacognostic Study of the Medicinal Flora of the USSR [in Russian], Sci. Works, Vol. XXV, Moscow (1987), pp. 126 – 131.Google Scholar
  4. 4.
    E. Z. Dzhakeli and V. Yu. Vachnadze, Georgian Medical News, No. 10, 73 – 76 (2002).Google Scholar
  5. 5.
    K. S. Mudzhiri, M. D. Gedevanishvili, V. Yu. Vachnadze, et al., USSR Pat. No. 879,849 (1981).Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2010

Authors and Affiliations

  • V. Yu. Vachnadze
    • 1
  • E. Z. Dzhakeli
    • 1
  • I. A. Dadeshidze
    • 1
  • L. G. Kintsurashvili
    • 1
  1. 1.Kutateladze Institute of Pharmaceutical ChemistryAcademy of Sciences of GeorgiaTbilisiRepublic of Georgia

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