A Reassessment of Prebiotic Organic Synthesis in Neutral Planetary Atmospheres
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The action of an electric discharge on reduced gas mixtures such as H2O, CH4 and NH3 (or N2) results in the production of several biologically important organic compounds including amino acids. However, it is now generally held that the early Earth’s atmosphere was likely not reducing, but was dominated by N2 and CO2. The synthesis of organic compounds by the action of electric discharges on neutral gas mixtures has been shown to be much less efficient. We show here that contrary to previous reports, significant amounts of amino acids are produced from neutral gas mixtures. The low yields previously reported appear to be the outcome of oxidation of the organic compounds during hydrolytic workup by nitrite and nitrate produced in the reactions. The yield of amino acids is greatly increased when oxidation inhibitors, such as ferrous iron, are added prior to hydrolysis. Organic synthesis from neutral atmospheres may have depended on the oceanic availability of oxidation inhibitors as well as on the nature of the primitive atmosphere itself. The results reported here suggest that endogenous synthesis from neutral atmospheres may be more important than previously thought.
KeywordsPrebiotic synthesis Neutral atmosphere Primitive Earth environment Miller–Urey experiment electric discharge
This work was supported by the University of California Institute for Mexico and the USA (UC MEXUS) Program and the NASA Specialized Center of Research and Training in Exobiology. Stanley L. Miller passed away during the final preparation of the manuscript. We dedicate this work to his memory.
- Annino JS, Giese RW (1976) Chapter 12, Nitrogenous compounds in clinical chemistry, principles and procedures, 4th edn. Little, Brown and Company, Boston, pp 157–160Google Scholar
- Gieskes JM, Gamo T, Brumsack H (1991) Chemical methods for interstitial water analysis aboard JOIDES resolution ocean drilling program, Texas A&M University Technical Note 15. p 48Google Scholar
- Haldane JBS (1928) The origin of life. Ration Annu 148:3–10Google Scholar
- Holland HD (1962) Model for the evolution of the earth’s atmosphere. In: Engle EJ, James HL, Leonard BF (eds) Petrologic studies: a volume in honor of A. G. Buddington. Geological Society of America, Boulder, pp 447–477Google Scholar
- Kasting JF (1993b) Early evolution of the atmosphere and ocean. In: Greenberg JM, Mendoza-Gomez CX, Pirronello V (eds) The chemistry of life’s origin. Kluwer Academic, Dordrecht, pp 149–176Google Scholar
- Miller SL (1998) The endogenous synthesis of organic compounds. In: Brack A (ed) The molecular origins of life: assembling pieces of the puzzle. Cambridge University Press, Cambridge, pp 59–85Google Scholar
- Robertson K, Williams P, Bada JL (1987) Acid hydrolysis of dissolved combined amino acids in seawater: a precautionary note. Limnol Oceanogr 32:996–997Google Scholar
- Strickland JDH, Parsons TR (1972) II.7. Determination of reactive nitrite, in Bulletin 167. In: Strickland JDH, Parsons TR (eds) A practical handbook of seawater analysis. 2nd edn. Fisheries Research Board of Canada, Ottawa, pp 77–80Google Scholar
- Wells J (2000) Icons of evolution. Regnery, Washington DC, p 338Google Scholar