Neurophysiology

, Volume 49, Issue 3, pp 234–236 | Cite as

Electrical Activity of the Cerebral Structures and Regulatory Effects of NO, Steroid Hormones, and BDNF in Rats with Experimental Alcohol Addiction

  • O. G. Berchenko
  • A. M. Titkova
  • O. V. Veselovs’ka
  • A. V. Shlyakhova
  • N. O. Levicheva
  • O. O. Prikhod’ko
PROCEEDINGS OF THE VII CONGRESS OF THE UKRAINIAN NEUROSCIENCE SOCIETY (Kyiv, June 7-11, 2017)
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In a chronic experiment on rats with induced alcohol addiction, it was shown that chronic alcoholization leads to decreases in the levels of cortisol and testosterone in the hypothalamus, amygdalar complex, and blood serum. Functional changes in the hippocampus and nucl. accumbens are believed to play a leading role in the formation of the alcohol withdrawal syndrome. Under these conditions, the level of NO metabolites in the above structures decreases against the background of increased BDNF concentrations in blood serum.

Keywords

electrical activity of brain structures nitric oxide cortisol testosterone BDNF alcohol dependence alcohol withdrawal syndrome 
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • O. G. Berchenko
    • 1
  • A. M. Titkova
    • 1
  • O. V. Veselovs’ka
    • 1
  • A. V. Shlyakhova
    • 1
  • N. O. Levicheva
    • 1
  • O. O. Prikhod’ko
    • 1
  1. 1.Institute of Neurology, Psychiatry, and Narcology, NAMS of UkraineKharkivUkraine

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