Neurophysiology

, Volume 45, Issue 5–6, pp 453–458 | Cite as

Hypoalgesia Induced by Preliminary Microwave Irradiation of an Acupuncture Point: Effects on Somatic Pain in Mice

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We studied the effects of preliminary irradiation of the acupuncture point (AP) E36 by low-intensity microwaves on experimentally evoked somatic pain in mice. Irradiation preceded induction of somatic pain in the formalin test, FT (subcutaneous injection of 25 μl 5% formalin solution into the dorsal surface of the foot).The FT was carried out in different groups of animals immediately, 10 min, and 20 min after termination of a period of microwave irradiation of the AP. Analgesic effects were observed in all examined animal groups within both acute and tonic pain phases. Normalized decreases in the duration of behavioral manifestations of the acute pain phase were equal to 57.7, 50.4, and 28.8% in the cases where the FT was realized immediately, 10 min, and 20 min after irradiation of the AP. For the tonic phase of the pain reaction, the respective figures were 49.6, 60.5, and 56.2%, respectively. Thus, irradiation of the AP E36 by low-intensity microwaves performed before the development of somatic pain exerts noticeably stronger hypoalgesic effects with respect to tonic somatic pain.

Keywords

acupuncture point (AP) microwaves somatic pain formalin test (FT) 
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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Bogomolets Institute of Physiology of the NAS of UkraineKyivUkraine

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