, Volume 38, Issue 4, pp 302–304 | Cite as

Synaptic connections in a dissociated mixed culture of rat dorsal root ganglion and spinal cord neurons

  • Yu. O. KolodinEmail author
  • A. O. Moskalyuk
  • N. S. Veselovsky
  • S. A. Fedulova


Postsynaptic currents and action potentials recorded from neurons in a mixed culture of rat dorsal root ganglion and spinal cord cells are described. The existence of mutual synaptic connections between the above two types of neurons is demonstrated.


mixed culture dorsal root ganglion spinal cord postsynaptic currents 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    O. P. Hamill, A. Marty, E. Neher, et al., “Improved patch-clamp techniques for high-resolution current recording from cell and cell-free membrane patches,” Pflügers Arch., 391, No. 2, 85–100 (1981).PubMedCrossRefGoogle Scholar
  2. 2.
    J. D. Clements and J. M. Bekkers, “Detection of spontaneous synaptic events with an optimally scaled template,” Biophys. J., 73, No. 1, 220–229 (1997).PubMedCrossRefGoogle Scholar
  3. 3.
    Yu. V. Medvedeva, N. S. Veselovsky, S. A. Fedulova, and P. G. Kostyuk, “Postsynaptic currents in dorsal root ganglion neurons co-cultured with spinal cord neurons,” Neurophysiology, 33, No. 1, 1–4 (2001).CrossRefGoogle Scholar
  4. 4.
    Yu. V. Medvedeva, S. A. Fedulova, and N. S. Veselovsky, “Synaptogenesis in co-culture of neurons of dorsal root ganglia and spinal cord,” Neurophysiology, 33, No. 6, 349–355 (2001).CrossRefGoogle Scholar
  5. 5.
    Y. Aoki, Y. Takahashi, S. Ohtori, et al., “Distribution and immunocytochemical characterization of dorsal root ganglion neurons innervating the lumbar intervertebral disc in rats: a review,” Life Sci., 74, No. 21, 2627–2642 (2004).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Yu. O. Kolodin
    • 1
    Email author
  • A. O. Moskalyuk
    • 1
  • N. S. Veselovsky
    • 1
  • S. A. Fedulova
    • 1
  1. 1.International Center for Molecular PhysiologyNational Academy of Sciences of UkraineKyivUkraine

Personalised recommendations