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Journal of Neuro-Oncology

, Volume 126, Issue 2, pp 219–224 | Cite as

Pituitary metastasis: is there still a place for neurosurgical treatment?

  • V. Gilard
  • C. Alexandru
  • F. Proust
  • S. Derrey
  • P. Hannequin
  • O. Langlois
Topic Review

Abstract

Pituitary metastases are uncommon, ranging from 1 to 5 % of all metastases. Between 10 and 30 % of pituitary lesions are symptomatic responsible for diabetes insipidus, visual field defect or cranial nerve palsy. Primary sites are lung or breast in two-thirds of cases. There is no current reference concerning treatment of such lesions. Overall survival is poor and depends on primary site. Although the role of surgery is currently limited, discussion is warranted in several indications for diagnostic or symptomatic purposes. We report two cases of symptomatic pituitary metastases in a context of breast cancer and review the litterature concerning the role of surgery and other treatment modalities.

Keywords

Pituitary gland- metastases Surgical treatment 

Notes

Acknowledgments

The authors are grateful to Nikki Sabourin-Gibbs, Rouen University Hospital, for her help in editing the manuscript.

Compliance with ethical standards

Conflict of interest

None.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of NeurosurgeryRouen University HospitalRouen CedexFrance
  2. 2.Department of OncologyHenri Becquerel Cancer CenterRouenFrance
  3. 3.Department of NeurosurgeryStrasbourg University HospitalStrasbourgFrance

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