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Journal of Neuro-Oncology

, Volume 99, Issue 2, pp 287–288 | Cite as

Multiple paraneoplastic diseases occurring in the same patient after thymomectomy

  • C. BrianiEmail author
  • A. Cagnin
  • S. Blandamura
  • G. Altavilla
Case Report

Abstract

Thymoma-associated paraneoplastic diseases include myasthenia gravis (MG), neuromyotonia (NMT), Morvan’s syndrome, and several non-neurological paraneoplastic manifestations, including glomerulonephritis. Paraneoplastic syndromes often precede the occurrence of thymoma, but cases occurring after thymomectomy, which sometimes herald the recurrence of thymoma, have also been described. We report on a patient who developed MG after thymomectomy for a malignant thymoma. After MG remission, NMT and Morvan’s syndrome occurred, which heralded a mediastinic recurrence, as demonstrated only by autopsy findings.

Keywords

Myasthenia gravis Neuromyotonia Paraneoplastic diseases Thymoma Morvan’s syndrome 

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Copyright information

© Springer Science+Business Media, LLC. 2010

Authors and Affiliations

  • C. Briani
    • 1
    Email author
  • A. Cagnin
    • 1
  • S. Blandamura
    • 2
  • G. Altavilla
    • 2
  1. 1.Departments of NeurosciencesUniversity of PadovaPadovaItaly
  2. 2.Medical Diagnostic Sciences and Special TherapiesUniversity of PaduaPadovaItaly

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