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Journal of Neuro-Oncology

, Volume 95, Issue 3, pp 433–435 | Cite as

Neuroradiological follow-up of the growth of papillary tumor of the pineal region: a case report

  • Alfonso CeraseEmail author
  • Ignazio Maria Vallone
  • Giovanni Di Pietro
  • Giuseppe Oliveri
  • Clelia Miracco
  • Carlo Venturi
Case Report

Abstract

Papillary tumor of the pineal region (PTPR) is a recently described distinct clinicopathological entity. The purpose of this case report is to increase the knowledge of its neuroradiological findings and natural history by describing the long-term clinical and neuroradiological follow-up of a PTPR occurring in a 56-year-old Italian male patient. At magnetic resonance imaging (MRI) obtained at diagnosis, the lesion showed a subtle high signal intensity on T1-weighted imaging. Twenty-nine months later, MRI showed clearcut enlargement of the lesion, which had only a small area of high signal intensity on T1-weighted images, and a minimum apparent diffusion coefficient of 0.854 × 10−3 mm2/s. Treatment included surgery followed by irradiation. Three-month MRI follow-up did not show disease relapse.

Keywords

Computed tomography Diffusion-weighted imaging Magnetic resonance imaging Pineal region tumors Papillary tumor of the pineal region 

Notes

Acknowledgments

We thank Tiziana Caselli from the Unit of Neuroimaging and Neurointervention, and Interdepartmental Center of Nuclear Magnetic Resonance, Azienda Ospedaliera Universitaria Senese, Policlinico “Santa Maria alle Scotte,” Siena, Italy, for her technical support, Ombretta Bugiani and Roberto Faleri from the Central Library, School of Medicine, University of Siena, Policlinico “Santa Maria alle Scotte,” Siena, Italy, for providing the pertinent references for the preparation of this paper.

References

  1. 1.
    Fèvre-Montange M, Hasselblatt M, Figarella-Branger D, Chauveinc L, Champier J, Saint-Pierre G, Luc Taillandier L, Coulon A, Paulus W, Fauchon F, Jouvet A (2006) Prognosis and histopathologic features in papillary tumors of the pineal region: a retrospective multicenter study of 31 cases. J Neuropathol Exp Neurol 65:1004–1111. doi: 10.1097/01.jnen.0000240462.80263.13 CrossRefPubMedGoogle Scholar
  2. 2.
    Jouvet A, Nakazato Y, Scheithauer BW, Paulus W (2007) Papillary tumour of the pineal region. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) WHO classification of tumours of the nervous system. IARC, Lyon, pp 128–129Google Scholar
  3. 3.
    Boco T, Aalaei S, Musacchio M, Byrne R, Cochran E (2008) Papillary tumor of the pineal region. Neuropathology 28:87–92. doi: 10.1111/j.1440-1789.2007.00832.x CrossRefPubMedGoogle Scholar
  4. 4.
    Smirniotopoulos JG, Rushing EJ, Mena H (1992) Pineal region masses: differential diagnosis. Radiographics 12:577–596CrossRefPubMedGoogle Scholar
  5. 5.
    Chang AH, Fuller GN, Debnam JM, Karis JP, Coons SW, Ross JS, Dean BL (2008) MR imaging of papillary tumor of the pineal region. AJNR Am J Neuroradiol 29:187–189. doi: 10.3174/ajnr.A0784 CrossRefPubMedGoogle Scholar
  6. 6.
    Santarius T, Joseph JA, Tsang KT, O’Donovan DG, Kirollos RW (2008) Papillary tumour of the pineal region. Br J Neurosurg 22:116–120. doi: 10.1080/02688690701583794 CrossRefPubMedGoogle Scholar
  7. 7.
    Sato TS, Kirby PA, Buatti JM, Moritani T (2009) Papillary tumor of the pineal region: report of a rapidly progressive tumor with possible multicentric origin. Pediatr Radiol 39:188–190. doi: 10.1007/s00247-008-1060-1 CrossRefPubMedGoogle Scholar
  8. 8.
    Inoue T, Kumabe T, Kanamori M, Sonoda Y, Watanabe M, Tominaga T (2008) Papillary tumor of the pineal region: a case report. Brain Tumor Pathol 25:85–90. doi: 10.1007/s10014-008-0231-y CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC. 2009

Authors and Affiliations

  • Alfonso Cerase
    • 1
    • 4
    Email author
  • Ignazio Maria Vallone
    • 1
    • 4
  • Giovanni Di Pietro
    • 2
  • Giuseppe Oliveri
    • 2
  • Clelia Miracco
    • 3
  • Carlo Venturi
    • 1
    • 4
  1. 1.Unit of Neuroimaging and NeurointerventionAzienda Ospedaliera Universitaria Senese, “Santa Maria alle Scotte” General HospitalSienaItaly
  2. 2.Unit of Neurosurgery, Department of NeurosciencesAzienda Ospedaliera Universitaria Senese, “Santa Maria alle Scotte” General HospitalSienaItaly
  3. 3.Department of Human Pathology, Section of Pathologic AnatomyUniversity of Siena, “Santa Maria alle Scotte” General HospitalSienaItaly
  4. 4.Interdepartmental Center of Nuclear Magnetic ResonanceAzienda Ospedaliera Universitaria Senese, “Santa Maria alle Scotte” General HospitalSienaItaly

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