Journal of Neuro-Oncology

, Volume 95, Issue 1, pp 147–150 | Cite as

Intracranial collision metastases of prostate and esophageal carcinoma

  • Sheri Dewan
  • Victor E. Alvarez
  • John E. Donahue
  • Deus Cielo
Case Report


Collision tumors are found when two pathologic tumor types are intermingled into a single location. Although these lesions have been reported in cases of metastases to primary intracranial tumors, there are very few case reports indentifying collision of primary malignancies outside of the central nervous system (CNS). We report a case of intracranial collision metastases to the brain with prostate and esophageal malignancies as the primary non-CNS tumors.

Case report

JB is a 72 year old male with a known history of esophageal and hormone refractory prostate cancer, both of which were diagnosed in 2006. He initially underwent chemoradiation with Taxol and cisplatin. Post-treatment esophageal biopsy revealed residual tumor; he therefore underwent esophagectomy. The original pathology was not available, however the tumor was compatible with CDX2, rendering other gastrointestinal carcinomas very unlikely.

In November of 2007 he presented with a several month history of...


Meningioma Pituitary Adenoma Esophageal Carcinoma Cardiac Tamponade Ganglioglioma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC. 2009

Authors and Affiliations

  • Sheri Dewan
    • 1
  • Victor E. Alvarez
    • 2
  • John E. Donahue
    • 2
  • Deus Cielo
    • 1
  1. 1.Department of NeurosurgeryWarren Alpert Medical School of Brown University and Rhode Island HospitalProvidenceUSA
  2. 2.Division of Neuropathology and Department of PathologyWarren Alpert Medical School of Brown University and Rhode Island HospitalProvidenceUSA

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