Intracranial collision metastases of prostate and esophageal carcinoma
Collision tumors are found when two pathologic tumor types are intermingled into a single location. Although these lesions have been reported in cases of metastases to primary intracranial tumors, there are very few case reports indentifying collision of primary malignancies outside of the central nervous system (CNS). We report a case of intracranial collision metastases to the brain with prostate and esophageal malignancies as the primary non-CNS tumors.
JB is a 72 year old male with a known history of esophageal and hormone refractory prostate cancer, both of which were diagnosed in 2006. He initially underwent chemoradiation with Taxol and cisplatin. Post-treatment esophageal biopsy revealed residual tumor; he therefore underwent esophagectomy. The original pathology was not available, however the tumor was compatible with CDX2, rendering other gastrointestinal carcinomas very unlikely.
KeywordsMeningioma Pituitary Adenoma Esophageal Carcinoma Cardiac Tamponade Ganglioglioma