Journal of Neuro-Oncology

, Volume 94, Issue 2, pp 293–296 | Cite as

Aggression in a patient with primary brain tumor: ethical implications for best management

  • J. Lee Villano
  • Nada Mlinarevich
  • Karriem S. Watson
  • Herbert H. Engelhard
  • Lisa Anderson-Shaw
Case Report


We present a case of a 55-year-old male diagnosed with glioblastoma (GB) involving the left frontal, parietal, and temporal lobes that developed aggression and committed a violent act against his wife. Aggression and violence have rarely been presented in the neuro-oncology literature, but have been well documented in stroke and dementia literature. We discuss the case along with the ethical principles as well as best management practices that may have been employed. As our therapies improve overall survival in brain tumors, aggression is an important behavior that the field must acknowledge.


Ethics Glioblastoma Aggression Violence Brain tumor 


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Copyright information

© Springer Science+Business Media, LLC. 2009

Authors and Affiliations

  • J. Lee Villano
    • 1
  • Nada Mlinarevich
    • 2
  • Karriem S. Watson
    • 2
  • Herbert H. Engelhard
    • 2
  • Lisa Anderson-Shaw
    • 3
  1. 1.Department of Medicine, Section of Hematology/OncologyUniversity of IllinoisChicagoUSA
  2. 2.Department of NeurosurgeryUniversity of IllinoisChicagoUSA
  3. 3.Department of Clinical EthicsUniversity of IllinoisChicagoUSA

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