Journal of Neuro-Oncology

, Volume 93, Issue 2, pp 261–262

A rare case of vomiting: fourth ventricular B-cell lymphoma

  • C. S. Hill
  • A. F. Khan
  • S. Bloom
  • S. McCartney
  • D. Choi
Case report

Abstract

We document the case of a 69-year-old man presenting with 6 weeks of intractable vomiting. Magnetic Resonance Imaging showed a homogenously enhancing mass in the caudal fourth ventricle. Surgical exploration and biopsy was performed and pathological examination demonstrated a high-grade B-cell lymphoma. The lesion was a primary tumour in an immuno-competent patient. Despite the increasing incidence of primary central nervous system lymphomas this is believed to be only the third ever case to have occurred at this rare site. We suggest that primary B-cell lymphoma should be considered with homogenous lesions of the fourth ventricle.

Keywords

Vomiting Lymphoma Fourth ventricle B-cell High-grade 

References

  1. 1.
    Central Brain Tumour Registry of United States (2007) Statistical report: primary brain tumours in the United States 2000–2004 (Years of data collected). Available via: http://www.cbtrus.org/reports/reports.html
  2. 2.
    Werneck LC, Hatschbach Z, Mora AH, Novarak EM (1977) Meningite por linfoma primitivo do sistema nervoso central. Relato de um case. Arq Neuropsiquiatr 35:366–372PubMedGoogle Scholar
  3. 3.
    Haegelen C, Riffaud L, Bernard M, Morandi X (2001) Primary isolated lymphoma of the fourth ventricle: case report. J Neurooncol 51:129–131. doi:10.1023/A:1010790325692 PubMedCrossRefGoogle Scholar
  4. 4.
    Hochberg FH, Baehring JM, Hochberg EP (2007) Primary CNS lymphoma. Nat Clin Pract Neurol 3:24–35. doi:10.1038/ncpneuro0395 PubMedCrossRefGoogle Scholar
  5. 5.
    Batchelor T, Carson K, O’Neill A, Grossman SA, Alavi J, New P, Hochberg F, Priet R (2003) Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96–07. J Clin Oncol 21:1044–1049. doi:10.1200/JCO.2003.03.036 PubMedCrossRefGoogle Scholar
  6. 6.
    Pirotte B, Levivier M, Goldman S, Brucher JM, Brotchi J, Hildebrand J (1997) Glucocorticoid-induced longterm remission in primary cerebral lymphoma: case report and review of the literature. J Neurooncol 32:63–69. doi:10.1023/A:1005733416571 PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • C. S. Hill
    • 1
  • A. F. Khan
    • 2
  • S. Bloom
    • 2
  • S. McCartney
    • 2
  • D. Choi
    • 3
  1. 1.Institute of Neurology (No7), National Hospital for Neurology and NeurosurgeryLondonUK
  2. 2.University College Hospital LondonLondonUK
  3. 3.Neurosurgical DepartmentNational Hospital for Neurology and NeurosurgeryLondonUK

Personalised recommendations