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Journal of Neuro-Oncology

, Volume 90, Issue 1, pp 25–30 | Cite as

Long-term outcome of conventional radiation therapy for central neurocytoma

  • Sun Ha Paek
  • Jung-Ho Han
  • Jin Wook Kim
  • Chul-Kee Park
  • Hee-Won Jung
  • Sung-Hye Park
  • Il Han Kim
  • Dong Gyu KimEmail author
Clinical-Patienet Studies

Abstract

The authors report the long-term outcome of conventional radiation therapy (RT) in six cases of central neurocytoma (CN). Between 1985 and 1992, six patients were treated with RT for residual tumors or for prevention of recurrence after surgery. The median follow-up period of radiological and clinical status were 171 (range: 128–229) and 202 months (range: 165–227), respectively. Tumors disappeared in three and reduced in three patients at the last follow-up. One-mortality case due to radiation necrosis and one radiation-induced malignancy occurred. White matter degeneration and cortical atrophy were noticed with slow progression of performance deterioration in two patients. Conventional RT seemed to effectively control residual CN after surgery. However, more sophisticated radiation techniques should be applied to minimize the late sequela.

Keywords

Central neurocytoma Conventional radiation therapy Long-term outcome 

Notes

Acknowledgments

This work was partially supported by a grant from Cancer Research Institute of Seoul National University and Clinical Research institute of Seoul National University Hospital.

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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Sun Ha Paek
    • 1
  • Jung-Ho Han
    • 1
  • Jin Wook Kim
    • 1
  • Chul-Kee Park
    • 1
  • Hee-Won Jung
    • 1
  • Sung-Hye Park
    • 2
  • Il Han Kim
    • 3
  • Dong Gyu Kim
    • 1
    Email author
  1. 1.Department of NeurosurgerySeoul National University College of Medicine, Cancer Research Center, Seoul National University, Clinical Research Institute, Seoul National University HospitalSeoulKorea
  2. 2.Department of PathologySeoul National University College of Medicine, Seoul National University, Clinical Research Institute, Seoul National University HospitalSeoulKorea
  3. 3.Department of Radiation OncologySeoul National University College of Medicine, Seoul National University, Clinical Research Institute, Seoul National University HospitalSeoulKorea

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