Journal of Neuro-Oncology

, Volume 89, Issue 1, pp 59–62

Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease

Clinical-patient studies

Abstract

Introduction Ollier Disease is a sporadic skeletal disorder with a predisposition to oncogenesis. It is estimated at around 1/100,000. We are presenting a young patient with Ollier Disease and high-grade astrocytoma. Case report A 14-year-old, Caucasian male with Ollier Disease presented with a history of headaches, vomiting, blurred vision, and unsteady gait. Brain MRI with contrast showed a 41 × 55 mm mass in the posterior fossa with spotty enhancement, which pathology proved to be anaplastic astrocytoma. Conclusion Despite the universal acceptance that Ollier Disease carries a high risk of developing malignancy there is very little in the literature about systematic screening. We recommended a cost-effective screening regime for these patients.

Keywords

Ollier Astrocytoma Screening PTHR1 PTEN 

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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  1. 1.Medical Center of Central GeorgiaMaconUSA
  2. 2.Greenville Hospital System University Medical CenterSoutheastern Neurosurgical & Spine InstituteGreenvilleUSA

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