Journal of Neuro-Oncology

, Volume 88, Issue 1, pp 37–41 | Cite as

Meningeal Castleman’s disease with multifocal involvement: a case report and review of literature

  • Santiago Coca
  • Isabel Salas
  • Roberto Martínez
  • Miguel Angel Saez
  • Jesús Vaquero
Clinical - patient Studies


Castleman’s disease is an uncommon lymphoproliferative disorder characterized by lymph node enlargement, hyperplasia of lymphoid follicles surrounded by mature lymphocytes, and capillary proliferation with endothelial hyperplasia. Although intracranial location is very uncommon, it should be considered in the differential diagnosis of meningeal tumors. We describe a new case appearing as two solid extraaxial masses simulating meningiomas. This multifocal meningeal involvement can be considered as an exceptional form of presentation of intracranial Castleman’s disease.


Castleman’s disease Meningeal tumors Brain tumor Lymphoproliferative disorder 


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Copyright information

© Springer Science+Business Media, LLC. 2008

Authors and Affiliations

  • Santiago Coca
    • 1
  • Isabel Salas
    • 2
  • Roberto Martínez
    • 3
  • Miguel Angel Saez
    • 1
  • Jesús Vaquero
    • 4
  1. 1.Department of PathologyHospital Central de la Defensa “Gomez Ulla”MadridSpain
  2. 2.Department of PathologyHospital Puerta de HierroMadridSpain
  3. 3.Department of Functional NeurosurgeryHospital Rúber InternacionalMadridSpain
  4. 4.Department of NeurosurgeryHospital Puerta de Hierro, Autonomous UniversityMadridSpain

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