Neuroscience and Behavioral Physiology

, Volume 49, Issue 3, pp 357–364 | Cite as

Synergistic Application of Zinc and Vitamin C to Support Memory and Attention and to Decrease the Risk of Developing Nervous System Diseases

  • O. A. GromovaEmail author
  • I. Yu. Torshin
  • A. V. Pronin
  • M. A. Kilchevsky

Provision of the body with zinc and vitamin C is important for CNS functioning. Zinc ions take part in neurotransmission (transmission of signals from acetylcholine, catecholamine, serotonin, and prostaglandin receptors) and in ubiquitin-dependent protein degradation. Zinc deficiency is associated with the development of Alzheimer’s disease and depression. Zinc supplementation (10–30 mg/day) improves neurological recovery in patients with stroke and closed craniocerebral injury and also improves measures of attention; it decreases hyperactivity in children. Vitamin C is a synergist of zinc which supports the antioxidant resources of the brain, synaptic activity, and detoxification. Vitamin C supplements at a dose of 130–500 mg/day are recommended for the prophylaxis of dementia and neurodegenerative pathology.


zinc vitamin C dementia neurodegenerative hyperactivity 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • O. A. Gromova
    • 1
    Email author
  • I. Yu. Torshin
    • 2
  • A. V. Pronin
    • 1
  • M. A. Kilchevsky
    • 1
  1. 1.Ivanovo State Medical Academy, Ministry of Health of the Russian FederationIvanovoRussia
  2. 2.Moscow Institute of Physics and Technology (State University)DolgoprudnyiRussia

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