Neuroscience and Behavioral Physiology

, Volume 49, Issue 1, pp 121–128 | Cite as

Efficacy of Music Therapy in the Rehabilitation of Stroke Patients

  • E. Z. YakupovEmail author
  • A. V. Nalbat
  • M. V. Semenova
  • K. A. Tlegenova

Objective. To assess the dynamics of recovery of motor, speech, and autonomous functions in patients with ischemic stroke (IS) using music therapy. Materials and methods. A total of 45 patients with IS in the basin of the right middle cerebral artery were studied. Patients were divided into three groups of 15 – the study group, the reference group, and the control group. Patients of the first and second groups were treated with and without a special set of exercises with musical accompaniment on days 3, 5, 7, and 9 of rehabilitation. Patients of the third group received standard basal physiotherapy and served as the control group. Changes in status were evaluated on the NIHSS, the Rivermead Mobility Index, the Action Research Arm Test (ARAT), and the modified speech function assessment scale on days 2, 4, 6, 8, and 10 of illness. Cardiorespiratory synchronization was studied from day 6 of illness. Results and conclusions. Music therapy was shown to be statistically significantly effective in relation to all study parameters. The authors take the view that the actions of this program may be based on neuroplasticity processes.


ischemic stroke neuroplasticity music therapy neurorehabilitation cardiorespiratory synchronization 


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  1. 1.
    O. S. Starodubtseva and S. V. Begicheva, “Analysis of the prevalence of stroke using information technology,” Fundament. Issled., 8, 424–427 (2012).Google Scholar
  2. 2.
    E. I. Gusev, V. I. Skvortsova, and L. V. Stakhovskaya, “The challenge of stroke in the Russian Federation: time for active collaboration,” Zh. Nevrol. Psikhiat., 8, 4–10 (2007).Google Scholar
  3. 3.
    A. N. Bogolepova and E. I. Chukanova, “The challenge of neuroplasticity in neurology,” Zh. Nevrol. Psikhiat., 8, 72–75 (2010).Google Scholar
  4. 4.
    I. V. Damulin and E. V. Ekusheva, “Neuroplasticity processes after stroke,” Nevrol. Neiropsikh. Psikhosom., 3, 69–74 (2014), doi: Scholar
  5. 5.
    S. A. Zhivolupov and I. N. Samartsev, “Neuroplasticity: pathophysiological aspects and the potential for therapeutic modulation,” Zh. Nevrol. Psikhiat., 4, 78–85 (2009).Google Scholar
  6. 6.
    M. Hallett, “Plasticity of the human motor cortex and recovery from stroke,” Brain Res. Rev., 36, No. 2–3, 169–174 (2001), doi: Scholar
  7. 7.
    R. Chen, L. Cohen, and M. Hallett, “Nervous system reorganization following injury,” Neuroscience, 111, No. 4, 761–773 (2002), doi: Scholar
  8. 8.
    B. Draganski and A. May, “Training-induced structural changes in the adult human brain,” Behav. Brain Res., 192, No. 1, 137–142 (2008), doi: Scholar
  9. 9.
    V. A. Epifanov, Sanogenetic Mechanisms of Nervous System Pathology, GEOTAR-Media, Moscow (2009).Google Scholar
  10. 10.
    V. A. Epifanov, Physiotherapy and Sports Medicine: Guidelines for Institutions, GEOTAR-Media, Moscow (2007). 2007.Google Scholar
  11. 11.
    C. Weiller and M. Rijntjes, “Learning, plasticity, and recovery in the central nervous system,” Exp. Brain Res., 128, No. 1–2, 134–138 (1999), doi: Scholar
  12. 12.
    N. Gogtay, J. Giedd, and L. Lusk et al., “Dynamic mapping of human cortical development during childhood through early adulthood,” Proc. Natl. Acad. Sci. USA, 101, No. 21, 8174–8179 (2004), doi: Scholar
  13. 13.
    V. I. Lomakin (ed.), Sociocultural Rehabilitation of Invalids: Methodological Guidelines, RIK, Moscow (2002).Google Scholar
  14. 14.
    C. Alain, S. Arnoot, S. Hevenor, S. Graham, and C. Gradually, “‘What’ and ‘where’ in the human auditory system,” Psychology, 98, 12301–12306 (2001).Google Scholar
  15. 15.
    S. Koelsch, T. Fritz, K. Schulze, D. Alsop, and G. Schlaug, “Adults and children processing music: An fMRI study,” Neuroimage, 25, No. 4, 1068–1076 (2005), doi: Scholar
  16. 16.
    A. Ivanitsky, A. Nikolaev, and G. Ivanitsky, “Cortical connectivity during word association search,” Internat. J. Psychophysiol., 42, No. 1, 35–53 (2001), doi: Scholar
  17. 17.
    N. N. Zaiko and Yu. V. Bytsya, Pathological Physiology, MEDpressinform, Moscow (2008).Google Scholar
  18. 18.
    I. M. Dogel’ and I. M. Sechenov, The Effects of Music in People and Animals, Kazan (1888).Google Scholar
  19. 19.
    V. I. Petrushin, Music Therapy: Theory and Practice, VLADOS, Moscow (1999).Google Scholar
  20. 20.
    B. Lyuban-Plotstsa, G. Poberezhnaya, and O. Belov, Music and the Mind. Listening with the Soul, ADEF-Ukraina, Kiev (2002).Google Scholar
  21. 21.
    S. V. Shushardzhan, Guidelines for Music therapy, Meditsina, Moscow (2005).Google Scholar
  22. 22.
    A. V. Pupysheva, Pedagogical Prophylaxis of Psychoemotional Disorders in Young Schoolchildren: Dissertation for Master’s Degree in Pediatric Sciences, Moscow (2014),, acc March 15, 2016.
  23. 23.
    W. Davis, K. Gfeller, and M. Thaut, An Introduction To Music Therapy, McGraw-Hill, Boston (1999).Google Scholar
  24. 24.
    J. Bradt, W. L. Magee, C. Dileo, B. L. Wheeler, and E. McGilloway, “Music therapy for acquired brain injury,” Cochrane Database Syst. Rev., 7, CD006787 (2010), doi: CrossRefGoogle Scholar
  25. 25.
    E. S. Petrosienko, “Effects of interhemisphere asymmetry on the activity of cardiovascular system functioning as a measure of tension on cardiac adaptational mechanisms,” Asimmetriya, 5, No. 3, 15–22 (2011).Google Scholar
  26. 26.
    O. V. Kurushina, A. E. Barulin, and O. V. Konovalova, “Correction of psychoemotional and autonomic impairments in patients with ischemic stroke,” Zh. Nevrol. Psikhiat., 9, No. 2, 50–54 (2013).Google Scholar
  27. 27.
    G. Gianotti and C. Caltagirone (eds), Emotions and Dual Brain, Springer, Berlin (1989).Google Scholar
  28. 28.
    A. Heigl-Evers, F. Heigl, J. Ott, and U. Ruger, Basic Handbook for Psychotherapy [Russian translation], M. M. Reshetnikov (ed.), Eastern European Institute for Psychoanalysis and Rech’, St. Petersburg (1998).Google Scholar
  29. 29.
    G. Decker-Voigt (ed.), Introduction to Music Therapy [Russian translation], Piter, St. Petersburg (2003).Google Scholar
  30. 30.
    L. S. Brusilovskii, Music Therapy: Guidelines for Psychotherapy, Moscow (2009).Google Scholar
  31. 31.
    A. N. Belova, Neurorehabilitation. Guidelines for Doctors, Moscow (2003).Google Scholar
  32. 32.
    N. Wiener, Cybernetics and Society [Russian translation], E. Ya. Coleman (ed.), Foreign Literature Press, Moscow (1958).Google Scholar
  33. 33.
    P. K. Anokhin, Essays on Functional Systems, Meditsina, Moscow (1975).Google Scholar
  34. 34.
    L. Criddle, C. Bonnono, and S. Fisher, “Standardizing stroke assessment using the National Institutes of Health Stroke Scale,” J. Emerg. Nurs., 29, No. 6, 541–546 (2003), doi: Scholar
  35. 35.
    S. Kasner, “Clinical interpretation and use of stroke scales,” Lancet Neurol., 5, No. 7, 603–612 (2006), doi: 70495-1.Google Scholar
  36. 36.
    J. Van der Lee, V. De Groot, H. Beckerman, R. Wagenaar, G. Lankhorst, and L. Bouter, “The intra- and interrater reliability of the Action Research Arm Test: A practical test of upper extremity function in patients with stroke,” Arch. Phys. Med. Rehabil., 82, No. 1, 14–19 (2001), doi: Scholar
  37. 37.
    E. G. Karaseva, Stuttering: Education and Methodological Manual, TOGIPPO, Tyumen, (2012).Google Scholar
  38. 38.
    F. Eckel and D. Boone, “The S/Z ratio as an indicator of laryngeal pathology,” J. Speech Hear. Disord., 46, No. 2, 147–149 (1981), doi: Scholar
  39. 39.
    J. Maslan, X. Leng, C. Rees, D. Blalock, and S. Butler, “Maximum phonation time in healthy older adults,” J. Voice, 25, No. 6, 709–713 (2011), doi: Scholar
  40. 40.
    V. M. Mikhailov, Variability in Heart Rate: Experience in Practical Application of the Method, Ivanovo State Medical Academy, Ivanovo (2002).Google Scholar
  41. 41.
    “Heart rate variability: standards of measurement, physiological interpretation, and clinical use,” Circulation, 93, No. 5, 1043–1065 (1996), doi:

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • E. Z. Yakupov
    • 1
  • A. V. Nalbat
    • 1
  • M. V. Semenova
    • 1
  • K. A. Tlegenova
    • 1
  1. 1.Kazan State Medical University, Ministry of Health of the Russian FederationKazanRussia

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