Neuroscience and Behavioral Physiology

, Volume 49, Issue 1, pp 13–19 | Cite as

Current Views on Chronic Pain and Its Relationship to the State of Sleep

  • M. L. Kukushkin
  • M. G. Poluektov

Chronic pain is a unique pathophysiological state characterized by the formation of stable neurotransmitter, morphological, and behavioral patterns. Sleep has a facilitating influence on many pain syndromes by blocking signal conduction via the nociceptive pathways, the release of specific neurotransmitters, and the lack of conscious perception during this period. Restriction to the duration of sleep and impairment to its structure are accompanied by increased pain, while improvements in sleep in some cases allow pain to be decreased.


sleep chronic pain insomnia 


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Authors and Affiliations

  1. 1.Research Institute of General Pathology and PathophysiologyRussian Academy of SciencesMoscowRussia
  2. 2.Sechenov First Moscow State Medical University (Sechenov University)MoscowRussia

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