Postnatal Morphogenesis of Purkinje Cells in the Rat Cerebellum
- 4 Downloads
Electron microscopic and histochemical methods were used to obtain a quantitative assessment of the development of organelles in Purkinje cells in the cerebellum of mongrel rats (n = 36) during the postnatal period of ontogeny (days 2, 7, 15, and 45). The nucleus:cytoplasm ratio decreased, while nucleolar area increased, the size and length of mitochondria increased, the quantity of membrane-bound ribosomes and the length of endoplasmic reticular channels increased, the number and sizes of lysosomes increased, and the relative area occupied by lysosomes on sections of the cytoplasm also increased.
Keywordscerebellum Purkinje cells ultrastructure morphometry
Unable to display preview. Download preview PDF.
- 1.K. P. Budko, N. G. Gladkovich, and E. V. Maksimova, Neuroontogenesis, Nauka, Moscow (1985).Google Scholar
- 2.O. A. Karnyushko and S. M. Zimatkin, “Impairments to the morphogenesis of the cerebellar cortex in the offspring of rats with experimental cholestasis and their correction,” Vestsi. NAN Belarusi. Ser. Med. Navuk., No. 3, 95–101 (2015).Google Scholar
- 3.S. N. Olenev, The Developing Brain, Nauka, Leningrad (1978).Google Scholar
- 7.M. A. Asari, M. S. Abdullan, and Z. I. Ismail, “Histomorphometric study on the effect of low dose deltamethrin on the developing cerebellar cortex,” Turk. J. Med. Sci., 40, and No. 6, 943–948 (2010).Google Scholar
- 8.O. J. Castejon, “Correlative microscopy of Purkinje cells,” Biocell, 35, No. 3, 1–29 (2011).Google Scholar
- 10.G. Millonig, “Advantages of a phosphate buffer or OsO4 solutions in fixation,” J. Appl. Physics., 32, 1637–1643 (1961).Google Scholar
- 11.G. Paxinos and C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, London (2007), 6th ed.Google Scholar