Neuroscience and Behavioral Physiology

, Volume 39, Issue 4, pp 323–328 | Cite as

Sequelae of Closed Craniocerebral Trauma and the Efficacy of Piracetam in Its Treatment in Adolescents

  • N. N. Zavadenko
  • L. S. Guzilova

The efficacy of piracetam in treating the sequelae of moderate and severe closed craniocerebral trauma (CCT) in adolescents was evaluated in studies of 42 patients aged 12–18 years who had suffered CCT 1.5–5 years prior to the study. Adolescents of the experimental group (20 individuals) received piracetam (Nootropil) at doses of 40–50 mg/kg (daily daily 1600–2400 mg) for one month; patients of group 2 (22 individuals) served as controls. Piracetam was found to have positive therapeutic effects on impairments to higher mental (memory, attention, executive) and motor (coordination) functions and on measures of the speeds of cognitive and motor operations.

Key Words

closed craniocerebral trauma adolescents sequelae long-term period treatment piracetam (Nootropil) 


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Copyright information

© Springer Science+Business Media, Inc. 2009

Authors and Affiliations

  • N. N. Zavadenko
    • 1
  • L. S. Guzilova
    • 1
  1. 1.Department of Neurology and Neurosurgery, Faculty of PediatricsRussian State Medical UniversityMoscowRussia

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