Nanomaterial registry: database that captures the minimal information about nanomaterial physico-chemical characteristics

  • Karmann C. Mills
  • Damaris Murry
  • Kimberly A. Guzan
  • Michele L. OstraatEmail author
Research Paper


Evaluating the implications of nanomaterials in biological and environmental systems can be difficult without sufficient characterization of the nanomaterials’ physico-chemical characteristics (PCC). Additionally, while nanomaterials possess inherent characteristics, their acquired characteristics can change based on the system under consideration or even the test method or protocol used for the characterization. The Nanomaterial Registry, an authoritative resource for nanomaterial data, has established minimal information about nanomaterials (MIAN) for PCC. The MIAN is used as a guideline for curating and archiving the nanomaterial information that is vital to understanding the biological and environmental implications of these materials. This manuscript details the MIAN developed and provides examples of curated data. The MIAN and Registry data model are flexible, and can accommodate new information and insights as scientific discovery regarding nanomaterials evolves. Through the use of the MIAN, the Registry archives sufficient metadata to allow the user to easily access the original/source study records of interest.


Nanomaterials Registry Nanoinformatics Minimal information about nanomaterials Environmental and biological implications 



RTI International would like to thank the National Institutes of Health (NIH) for funding this work, under contract HHSN268201000022C. The particular agencies advising this work are the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the National Institute of Environmental Health Sciences (NIEHS), and the National Cancer Institute (NCI).


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Karmann C. Mills
    • 1
  • Damaris Murry
    • 1
  • Kimberly A. Guzan
    • 1
  • Michele L. Ostraat
    • 1
  1. 1.RTI InternationalResearch Triangle ParkUSA

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