Nanomaterial registry: database that captures the minimal information about nanomaterial physico-chemical characteristics
- 317 Downloads
Evaluating the implications of nanomaterials in biological and environmental systems can be difficult without sufficient characterization of the nanomaterials’ physico-chemical characteristics (PCC). Additionally, while nanomaterials possess inherent characteristics, their acquired characteristics can change based on the system under consideration or even the test method or protocol used for the characterization. The Nanomaterial Registry, an authoritative resource for nanomaterial data, has established minimal information about nanomaterials (MIAN) for PCC. The MIAN is used as a guideline for curating and archiving the nanomaterial information that is vital to understanding the biological and environmental implications of these materials. This manuscript details the MIAN developed and provides examples of curated data. The MIAN and Registry data model are flexible, and can accommodate new information and insights as scientific discovery regarding nanomaterials evolves. Through the use of the MIAN, the Registry archives sufficient metadata to allow the user to easily access the original/source study records of interest.
KeywordsNanomaterials Registry Nanoinformatics Minimal information about nanomaterials Environmental and biological implications
RTI International would like to thank the National Institutes of Health (NIH) for funding this work, under contract HHSN268201000022C. The particular agencies advising this work are the National Institute of Biomedical Imaging and Bioengineering (NIBIB), the National Institute of Environmental Health Sciences (NIEHS), and the National Cancer Institute (NCI).
- American Society for Testing and Materials (2013) ASTM E2909-13—Standard guide for investigation/study/assay tab-delimited format for nanotechnologies (ISA-TAB-Nano): standard file format for the submission and exchange of data on nanomaterials and characterizations. Retrieved: 2013Google Scholar
- Hackley VA, Fritts M, Kelly JF, Patri AK, Rawle AF (2009) Enabling standards for nanomaterial characterization. INFOSIM 7:24–29 Google Scholar
- Hey T, Trefethen A (2003) The data deluge: an e-Science perspective. In: Berman F, Fox G, Hey J (eds) Grid computing—making the global infrastructure a reality. Wiley, New York, pp 809–824Google Scholar
- Hull M, Bowman D (2009) Nanotechnology environmental health and safety: risks, regulation and management, E-reader version. Elsevier, AmsterdamGoogle Scholar
- International Organization for Standardization (2012) ISO/TS 27687:2008 Nanotechnologies—terminology and definitions for nano-objects—nanoparticle, nanofibre and nanoplate. From: international organization for standardization http://www.iso.org/iso/home/store/catalogue_tc/catalogue_detail.htm?csnumber=44278. Accessed 2012
- Organization for Economic Co-operation and Development (2010) ENV/JM/MONO(2009)20/REV—guidance manual for the testing of manufactured nanomaterials: OECD’s sponsorship programme; first revision. From: organization for economic co-operation and development http://search.oecd.org/officialdocuments/displaydocumentpdf/?cote=env/jm/mono%282009%2920/rev&doclanguage=en. Accessed 2012
- Ostraat ML, Mills KC, Guzan KA, Murry D (2013) The nanomaterial registry: facilitating the sharing and analysis of data in the diverse nanomaterial community. Int J Nanomed 8(Suppl 1):1–7Google Scholar
- Sayes CM, Warheit DB (2009) Characterization of nanomaterials for toxicity assessment. Wiley Interdiscip Rev Nanomed Nanobiotechnol 1(6):660–670Google Scholar
- Sayes CM, Reed KL, Warheit DB (2007) Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulminary toxicity profiles. Toxicol Sci 97(1):63–180Google Scholar
- The Minimum Information for Nanomaterial Characterization Initiative (2008) The parameters list. Retrieved from the minimum information for nanomaterial characterization initiative: http://characterizationmatters.org/parameters/
- The Minimum Information for Nanomaterial Characterization Initiative (2012) http://characterizationmatters.org/