In situ thermolysis of magnetic nanoparticles using non-hydrated iron oleate complex

Research Paper
First Online:
Received:
Accepted:

Abstract

A novel strategy for the fabrication of nanostructured materials based on preparation of metallic surfactants is presented and some examples are demonstrated in this article. The suggested synthetic procedure of metal oleate is universal, potentially able to produce bulk quantities, and can be applicable to the synthesis of other metal oxide and metal nanoparticles. In general, organometallic compounds are quite expensive and are mostly classified as a highly toxic substance. In this study, we used simple, inexpensive, and eco-friendly approaches to prepare the metallic surfactants. As an example, non-hydrated iron oleate (FeOl) complexes are prepared as precursors for the in situ-fabricated superparamagnetic iron oxide nanoparticles (SPIONs) by thermolysis. The different coordination of the non-hydrated FeOl complexes are directly relating to the competition between nucleation and crystal growth. The in situ preparation of SPIONs involves the reaction of metal nitrate and carboxylic acid at 120 °C to synthesize the non-hydrated FeOl complexes and following the thermolysis of FeOl at 300 °C in non-coordination solvent. The coordination modes and distinct thermal behaviors of intermediates non-hydrated FeOl complexes are comparatively investigated by means of thermo-analytic techniques complimented by differential scanning calorimetry, thermal gravimetric analysis (TGA) and infrared spectroscopy (FTIR). The potential chemical structures of non-hydrated FeOl and their reaction mechanism by thermolysis were elucidated. The resulting lipid-coated SPIONs were characterized by transmission electron microscope, FTIR, differential temperature analysis, and TGA. These data suggested a bimodal interaction of organic shell and nanoparticle surface, with chemically absorbed inner layer and physically absorbed outer layer of carboxylic acid.

Keywords

Superparamagnetic Iron oxide SPIONs Iron oleate Monodispersed Thermolysis Ferrofluids Metallic surfactants Nanomaterials fabrication 
This is a preview of subscription content, log in to check access.

Notes

Acknowledgments

This study is supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant No. 2011-0013675).

Supplementary material

11051_2011_688_MOESM1_ESM.doc (1.4 mb)
Supplementary material 1 (DOC 1445 kb)

References

  1. Bronstein LM, Huang X, Retrum J, Schmucker A, Pink M, Stein BD, Dragnea B (2007) Chem Mater 19(15):3624–3632CrossRefGoogle Scholar
  2. Casula MF, Jun YW, Zaziski DJ, Chan EM, Corrias A, Alivisators AP (2006) J Am Chem Soc 128(5):1675–1677CrossRefGoogle Scholar
  3. Deng H, Li X, Peng Q, Wang X, Chen J, Li Y (2005) Angew Chem Int Ed Engl 44(18):2782–2785CrossRefGoogle Scholar
  4. Feng JH, Zhao J, Hao FH, Chen C, Bhakoo K, Tang HR (2011) NMR-based metabonomic analyses of the effects of ultrasmall superparamagnetic particles of iron oxide (USPIO) on macrophage metabolism. J Nanopart Res 13(5):2049–2062. doi: 10.1007/s11051-010-9959-5 CrossRefGoogle Scholar
  5. Hyeon T, Lee SS, Park J, Chung Y, Na HB (2001) J Am Chem Soc 123(51):12798–12801CrossRefGoogle Scholar
  6. Jeon BS, Cho EJ, Yang HM, Suh JS, Huh YM, Kim JD (2009) Controlled aggregates of magnetite nanoparticles for highly sensitive MR contrast agent. J Nanosci Nanotechnol 9(12):7118–7122. doi: 10.1166/jnn.2009.1605 Google Scholar
  7. Kim DK, Dobson J (2009) Nanomedicine for targeted drug delivery. J Mater Chem 19(35):6294–6307. doi: 10.1039/b902711b CrossRefGoogle Scholar
  8. Kwon SG, Piao Y, Park J, Angappane S, Jo Y, Hwang NM, Park JG, Hyeon T (2007) J Am Chem Soc 129(41):12571–12584CrossRefGoogle Scholar
  9. Lee JS, Rodriguez-Luccioni HL, Mendez J, Sood AK, Lpez-Berestein G, Rinaldi C, Torres-Lugo M (2011) Hyperthermia induced by magnetic nanoparticles improves the effectiveness of the anticancer drug cis-diamminedichloroplatinum. J Nanosci Nanotechnol 11(5):4153–4157. doi: 10.1166/jnn.2011.3821 CrossRefGoogle Scholar
  10. Li Z, Wei L, Gao MY, Lei H (2005) Adv Mater 17(8):1001–1005CrossRefGoogle Scholar
  11. Mahajan SV, Dikerson JH (2007) Nanotechnol 18(32):325605–325611CrossRefGoogle Scholar
  12. Park J, An K, Hwang Y, Park JG, Noh HJ, Kim JY, Park JH, Hwang NM, Hyeon T (2004) Nat Mater 3:891–895CrossRefGoogle Scholar
  13. Roca AG, Morales MP, O’Grady K, Serna CJ (2006) Nanotechnol 17(11):2783–2788CrossRefGoogle Scholar
  14. Shukla N, Liu C, Jones PM, Weller D (2003) J Magn Magn Mater 266(1–2):178–184CrossRefGoogle Scholar
  15. Simioni AR, Rodrigues MMA, Primo FL, Morais PC, Tedesco AC (2011) Effect of diode-laser and AC magnetic field of bovine serum albumin nanospheres loaded with phthalocyanine and magnetic particles. J Nanosci Nanotechnol 11(4):3604–3608. doi: 10.1166/jnn.2011.3724 CrossRefGoogle Scholar
  16. Sun S, Zeng H (2002) J Am Chem Soc 124(28):8204–8205CrossRefGoogle Scholar
  17. Wang FH, Yoshitake T, Kim DK, Muhammed M, Bjelke O, Kehr J (2003) Determination of conjugation efficiency of antibodies and proteins to the superparamagnetic iron oxide nanoparticles by capillary electrophoresis with laser-induced fluorescence detection. J Nanopart Res 5(1–2):137–146. doi: 10.1023/a:1024428417660 CrossRefGoogle Scholar
  18. Yeh CH, Hsiao JK, Wang JL, Sheu F (2010) Immunological impact of magnetic nanoparticles (Ferucarbotran) on murine peritoneal macrophages. J Nanopart Res 12(1):151–160. doi: 10.1007/s11051-009-9589-y CrossRefGoogle Scholar
  19. Yu WY, Falkner JC, Yavuz CT, Colvin VL (2004) Chem Comm 20:2306–2307CrossRefGoogle Scholar
  20. Zobril R, Bakandritsos A, Mashlan M, Tzitzios V, Dallas P, Trapalis C, Petridis D (2008) Nanotechnol 19(9):095602–095610CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  1. 1.Department of Chemical EngineeringTsinghua UniversityBeijingChina
  2. 2.Department of Biomedical ScienceJungwon UniversityGoesanSouth Korea

Personalised recommendations