Journal of Nanoparticle Research

, Volume 13, Issue 8, pp 3413–3421 | Cite as

Redispersion of dried gold nanorods in the presence of 6-amino-1-hexanethiol hydrochloride

  • Kanako Honda
  • Hirofumi Kawazumi
  • Naotoshi Nakashima
  • Yasuro Niidome
Research paper
First Online:
Received:
Accepted:

Abstract

Aggregates of phosphatidylcholine-passivated gold nanorods were prepared by the addition of hydrochloric acid in the presence of 6-amino-1-hexanethiol hydrochloride (AHT). The aggregates dried in vacuum formed a solid film showing a metallic gold color. In spite of the absence of the stable surface-wrapping agents, such as balky polymer or thiol-molecules that form stable self-organized films on a gold surface, the dried aggregates dispersed again in water. The redispersed gold nanorods in water did not form aggregates. If the dried nanorods were kept at room temperature for 24 h, they did not disperse in water again; however, at –30 °C, some of gold nanorods could be redispersed in water. At –80 °C, gold nanorods could be redispersed in water as colloidal nanoparticles even after 2 months. The phosphatidylcholine and AHT molecules on the nanorod surfaces contributed to the suppression of the contact of nanorods, which were in the metallic gold color films.

Keywords

Gold nanorods Localized surface plasmon resonance Metal nanoparticles Colloids Aggregation 
This is a preview of subscription content, log in to check access.

Notes

Acknowledgments

This study was supported by a Grant-in-Aid for Scientific Research (No. 15350085), KAKENHI (Grant-in-Aid for Scientific Research) on priority area “Strong Photon-Molecule Coupling Fields (No. 470),” and a Grant-in-Aid for the Global COE Program “Science for Future Molecular Systems” from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of the Japanese Government.

References

  1. Brust M, Walker M, Bethell D, Schiffrin D J, Whyman R (1994) Synthesis of thiol-derivatised gold nanoparticles in a two-phase liquid–liquid system. J Chem Soc Chem Commun: 801–802Google Scholar
  2. Chen C-C, Lin Y-P, Wang C-W, Tzeng H-C, Wu C-H, Chen Y-C, Chen C-P, Chen L-C, Wu Y-C (2006) DNA-gold nanorods conjugates for remote control of localized gene expression by near infrared irradiation. J Am Chem Soc 128:3709–3715CrossRefGoogle Scholar
  3. Collier CP, Saykally RJ, Shiang JJ, Henrichs SE, Heath JR (1997) LB film Ag nanoparitlce, Heath. Science 277:5334CrossRefGoogle Scholar
  4. Daniel M-C, Astruc D (2004) Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-properties, and applications toward biology, catalysis, and nanotechnology. Chem Rev 104:293–346CrossRefGoogle Scholar
  5. Elghanian R, Storhoff JJ, Mucic RC, Letsinger RL, Mirkin CA (1997) Selective colorimetric detection of polynucleotides base on the distance-dependent optical properties of gold nanoparticles. Science 277:1078–1081CrossRefGoogle Scholar
  6. Gao J, Bender CM, Murphy CJ (2003) Dependence of the gold nanorod aspect ratio on the nature of the directing surfactant in aqueous solution. Langmuir 19:9065–9070CrossRefGoogle Scholar
  7. Gluodenis M, Foss CA Jr (2002) The effect of mutual orientation on the spectra of metal nanoparticles rod–rod and rod–sphere pairs. J Phys Chem B 106:9484–9489CrossRefGoogle Scholar
  8. Gole A, Murphy CJ (2005) Polyelectrolyte-coated gold nanorods: synthesis, characterization and immobilization. Chem Mater 17:1325–1330CrossRefGoogle Scholar
  9. Honda K, Niidome Y, Nakashima N, Kawazumi H, Yamada S (2006) End-to-end assemblies of gold nanorods adsorbed on a glass substrate modified with polyanion polymers. Chem Lett 35:852–853CrossRefGoogle Scholar
  10. Honda K, Kawazumi H, Yamada S, Nakashima N, Niidome Y (2007) Extraction of hexadecytrimethylammonium bromide from gold nanorod solutions: adsorption of gold nanorods on anionic glass surfaces. Trans Mater Res Soc Jpn 32:421–424Google Scholar
  11. Horiguchi Y, Niidome T, Yamada S, Nakashima N, Niidome Y (2007) Expression of plasmid DNA released from DNA conjugates of gold nanorods. Chem Lett 36:952–953CrossRefGoogle Scholar
  12. Horiguchi Y, Yamashita S, Niidome T, Nakashima N, Niidome Y (2008) Photoinduced release of oligonucleotide-conjugated silica-coated gold nanorods accompanied by moderate morphological changes. Chem Lett 37:718–719CrossRefGoogle Scholar
  13. Huang X, El-Sayed IH, Qian W, El-Sayed MA (2006) Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J Am Chem Soc 128:2115–2120CrossRefGoogle Scholar
  14. Jain PK, Eustis S, El-Sayed MA (2006a) Plasmon coupling in nanorod assemblies: optical absorption, discrete dipole approximation simulation, exciton-coupling model. J Chem Phys B 110:18243–18253CrossRefGoogle Scholar
  15. Jain PK, Lee KS, El-Sayed IH, El-Sayed MA (2006b) Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: application in biological imaging and biomedicine. J Phys Chem B 110:7238–7248CrossRefGoogle Scholar
  16. Kawano T, Yamagata M, Takahashi H, Niidome Y, Yamada S, Katayama Y, Niidome T (2006) Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses. J Control Release 111:382–389CrossRefGoogle Scholar
  17. Kawano T, Niidome Y, Mori T, Katayama Y, Niidome T (2009) PNIPAM gel-coated gold nanorods for targeted delivery responding to a near-infrared laser. Bioconjugate Chem 20:209–212CrossRefGoogle Scholar
  18. Kreibig U, Vollmer M (1994) Optical properties of metal clusters. Springer, BerlinGoogle Scholar
  19. Link S, El-Sayed MA (1999) Spectral properties and relaxation dynamics of surface plasmon electronic oscillation in gold and silver nanodots and nanorods. J Phys Chem B 103:8410CrossRefGoogle Scholar
  20. Link S, El-Sayed MA (2005) Simulation of the optical absorption spectra of gold nanorods as a function of their aspect ratio and the effect of the medium dielectric constant. J Phys Chem B 109:10531–10532CrossRefGoogle Scholar
  21. Link S, Mohamed MB, El-Sayed MA (1999) Simulation of the optical absorption spectra of gold nanorods as a function of their aspect ratio and the effect of the medium dielectric constant. J Phys Chem B 103:3073–3077CrossRefGoogle Scholar
  22. Markovich G, Collier CP, Heath JR (1998) Reversible metal–insulator transition in ordered metal nanocrystal monolayers observed by impedance spectroscopy. Phys Rev Lett 80:3807–3810CrossRefGoogle Scholar
  23. Markovich G, Collier CP, Henrichs SE, Remacle F, Levine PD (1999) Architectonic quantum dot solids. Acc Chem Res 32:415CrossRefGoogle Scholar
  24. Mie G (1908) Beiträge zur Optik trüber Medien, speziell kolloidaler Metallösungen. Ann Phys (Lipzig) 25:377CrossRefGoogle Scholar
  25. Mirkin CA, Letsinger RL, Mucic RC, Storhoff JJ (1996) A DNA-based method for rationally assembling nanoparticles into macroscopic materials. Nature 382:607–609CrossRefGoogle Scholar
  26. Murphy CJ, Gole AM, Hunyadi SE, Stone JW, Sisco PN, Alkilany A, Kinard BE, Hankins P (2008) Chemical sensing and imaging with metallic nanorods. Chem Commun: 544–557Google Scholar
  27. Niidome Y, Nishioka K, Kawasaki H, Yamada S (2003) Rapid synthesis of gold nanorods by the combination of chemical reduction and photoirradiation processes. Chem Commun: 2376–2377Google Scholar
  28. Niidome T, Yamagata M, Okamoto Y, Akiyama Y, Takahashi H, Kawano T, Katayama Y, Niidome Y (2006) PEG-modified gold nanorods with a stealth character for in vivo application. J Control Release 114:343–347CrossRefGoogle Scholar
  29. Niidome Y, Honda K, Higashimoto K, Kawazumi H, Yamada S, Nakashima N, Sasaki Y, Ishida Y, Kikuchi J (2007) Surface modification of gold nanorods with synthetic cationic lipids. Chem Commun: 3777–3779Google Scholar
  30. Niidome T, Akiyama Y, Shimoda K, Kawano T, Mori T, Katayama Y, Niidome Y (2008) In vivo monitoring of intravenously injected gold nanorods using near-infrared light. Small 4:1001–1007CrossRefGoogle Scholar
  31. Niidome Y, Nakamura Y, Honda K, Akiyama Y, Nishioka K, Kawasaki H, Nakashima N (2009) Characterization of silver ions adsorbed on gold nanorods: surface analysis by using surface-assisted laser desorption/ionization time-of-flight mass spectroscopy. Chem Commun: 1754–1756Google Scholar
  32. Niidome T, Ohga A, Akiyama Y, Watanabe K, Niidome Y, Mori T, Katayama Y (2010) Controlled release of PEG chain from gold nanorods: targeted delivery to tumor. Bioorg Med Chem 18:4453–4458CrossRefGoogle Scholar
  33. Nikoobakht B, El-Sayed MA (2001) Evidence for bilayer assembly of cationic surfactants on the surface of gold nanorods. Langmuir 17:6368–6374CrossRefGoogle Scholar
  34. Oyelere AK, Chen PC, Huang X, El-Sayed IH, El-Sayed MA (2007) Peptide-conjugated gold nanorods for nuclear targeting. Bioconj Chem 18:1490–1497CrossRefGoogle Scholar
  35. Pastoriza-Santos I, Pérez-Juste J, Liz-Marzán LM (2006) Silica-coating and hydrophobation of CTAB-stabilized gold nanorods. Chem Mater 18:2465–2467CrossRefGoogle Scholar
  36. Pérez-Juste J, Pastoriza-Santos I, Liz-Marzán LM, Mulvaney P (2005a) Gold nanorods: synthesis, characterization and applications. Coord Chem Rev 249:1870–1901CrossRefGoogle Scholar
  37. Pérez-Juste J, Rodríguez-Gonzárez B, Mulvaney P, Liz-Marzán LM (2005b) Optical control and patterning of gold-nanorod-poly(vinyl alcohol) nanocomposite. Adv Func Mater 15:1065–1071CrossRefGoogle Scholar
  38. Pietrobon B, Mceachran M, Kitaev V (2009) Synthesis of size-controlled faceted pentagonal silver nanorods with tunable plasmonic properties and self-assembly of these nanorods. ACS Nano 3:21–26CrossRefGoogle Scholar
  39. Sato K, Hosokawa K, Maeda M (2003) Rapid aggregation of gold nanoparticles induced by non-cross-linking DNA hybridization. J Am Chem Soc 125:8102–8103CrossRefGoogle Scholar
  40. Shiotani A, Mori T, Niidome T, Niidome Y, Katayama Y (2007) Stable incorporation of gold nanorods into N-isopropylacrylamide hydrogels and their rapid shrinkage induced by near-IR laser irradiation. Langmuir 23:4012–4018CrossRefGoogle Scholar
  41. Storhoff JJ, Elghanian R, Mucic RC, Mirkin CA, Letsinger RL (1998) One-pot colorimetric differentiation of polynucletotides with single base imperfections using gold nanoparticles. J Am Chem Soc 120:1959–1964CrossRefGoogle Scholar
  42. Storhoff JJ, Lazarides AA, Mucic RC, Mirkin CA, Letsinger RL, Schatz GC (2000) What controls the optical properties of DNA-linked gold nanoparticle assemblies? J Am Chem Soc 122:4640–4650CrossRefGoogle Scholar
  43. Takahashi H, Niidome Y, Yamada S (2005) Controlled release of plasmid DNA from gold nanorods induced by pulsed near-infrared light. Chem Commun: 2247–2249Google Scholar
  44. Takahashi H, Niidome T, Nariai A, Niidome Y, Yamada S (2006a) Gold nanorod-sensitized cell death: microscopic observation of single living cells irradiated by pulsed near-infrared laser light in the presence of gold nanorods. Chem Lett 35:500–501CrossRefGoogle Scholar
  45. Takahashi H, Niidome T, Nariai A, Niidome Y, Yamada S (2006b) Photothermal reshaping of gold nanorods prevents further cell death. Nanotechnology 17:4431–4435CrossRefGoogle Scholar
  46. Takahashi H, Niidome Y, Niidome T, Kaneko K, Kawasaki H, Yamada S (2006c) Modification of gold nanorods using phosphatidylcholine to reduce cytotoxicity. Langmuir 22:2–5CrossRefGoogle Scholar
  47. Vial S, Pastoriza-Santos S, Pétrez-Juste J, Liz-Marzán LM (2007) Plasmon coupling in layer-by-layer assembled gold nanorod films. Langmuir 23:4606–4611CrossRefGoogle Scholar
  48. Wang C, Ma Z, Wang T, Su Z (2006) Synthesis, assembly, and biofunctionalization of silica coated gold nanorods for colorimetric biosensign. Adv Func Mater 16:1673–1678CrossRefGoogle Scholar
  49. Yamashita S, Niidome Y, Katayama Y, Niidome T (2009) Photochemical reaction of poly(ethylenegrycol) on gold nanorods induced by near infrared pulsed-laser irradiation. Chem Lett 38:731–734Google Scholar
  50. Yu Y-Y, Chang S-S, Lee C-L, Wang CRC (1997) Gold nanorods: electrochemical synthesis and optical properties. J Phys Chem B 101:6661–6664CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Kanako Honda
    • 1
  • Hirofumi Kawazumi
    • 1
  • Naotoshi Nakashima
    • 2
  • Yasuro Niidome
    • 2
  1. 1.Department of Biological and Environmental ChemistryKinki University-KyushuIizukaJapan
  2. 2.Department of Applied ChemistryKyushu UniversityFukuokaJapan

Personalised recommendations