Journal of Nanoparticle Research

, Volume 10, Issue 4, pp 559–566

Biomimetic synthesis of HgS nanoparticles in the bovine serum albumin solution

  • De Zhi Qin
  • Xiao Ming Ma
  • Lin Yang
  • Li Zhang
  • Zhong Jun Ma
  • Jie Zhang
Research Paper


HgS nanocrystals conjugated with protein were synthesized in aqueous solution of Bovine Serum Albumin (BSA) at room temperature. The obtained HgS nanoparticles with average diameter about 20–40 nm were characterized by powder X-ray diffraction (XRD), transmission electron microscopy (TEM), selected-area electron diffraction (SAED) and high-resolution transmission electron microscopy (HRTEM). The quantum-confined effect of the HgS nanoparticles is confirmed by the ultraviolet-visible (UV-vis) and photoluminescence (PL) spectrum. The rescults indicate that the BSA not only induce the nucleation, but inhibit the further growth of HgS nanoparticles. The effect of Hg2+ on BSA and the change of BSA conformation were studied through Fourier transform infrared (FTIR) spectroscopy and Circular dichroism (CD) spectroscopy. The possible mechanism of HgS nanoparticles growth in the BSA solution was also discussed.


Mercury(II) sulfide Nanoparticles Biomimetic synthesis BSA Colloids Nanobiotechnology 


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Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  • De Zhi Qin
    • 1
    • 2
  • Xiao Ming Ma
    • 1
  • Lin Yang
    • 1
  • Li Zhang
    • 2
  • Zhong Jun Ma
    • 1
  • Jie Zhang
    • 1
  1. 1.College of Chemistry and Environmental ScienceHenan Normal UniversityXinxiangChina
  2. 2.College of Chemistry and Chemical EngineeringPingdingshan UniversityPindingshanChina

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