Natural Computing

, Volume 13, Issue 4, pp 559–572 | Cite as

Enforcing logical delays in DNA computing systems

  • Nathanaël Aubert
  • Yannick Rondelez
  • Teruo Fujii
  • Masami Hagiya


DNA computing has the potential to create powerful devices, but, in the context of well-mixed systems, sequentiality of operations is hard to achieve. To enforce such sequentiality, we propose a generic delay gate that can be interfaced with virtually any DNA system. Since it is system-independent, our delay gate can be used as an off-the-shelf library to accelerate the design of increasingly complex systems. Additionally, we checked the feasibility of our design by testing various in vitro implementations. We also present a theoretical proof of concept of its applicability by using it to complement an existing DNA module library, the DNA toolbox, to design new systems.


DNA computing Delay mechanism Sequentiality Concurrency DNA toolbox 


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Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Nathanaël Aubert
    • 1
  • Yannick Rondelez
    • 2
  • Teruo Fujii
    • 2
  • Masami Hagiya
    • 1
  1. 1.Graduate School of Information Science and TechnologyUniversity of TokyoTokyoJapan
  2. 2.LIMMS/CNRS-IIS, Institute of Industrial ScienceUniversity of TokyoTokyoJapan

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