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Mixed Infection of Toe Nail Caused by Trichosporon asahii and Rhodotorula mucilaginosa

  • Nur Fazleen Binti Idris
  • Guowang Huang
  • Qianying Jia
  • Lin Yuan
  • Yimin Li
  • Zeng TuEmail author
Short Communication
  • 48 Downloads

Abstract

Trichosporon asahii and Rhodotorula mucilaginosa are important fungal species causing disseminated disease in immunocompromised patients. Onychomycosis prevalence rate ranges from 2 to 30%, which were 50% of nail diseases and 30% of superficial mycosis, respectively. Although important, little is known about the co-habitation of T. asahii and R. mucilaginosa in the causation of onychomycosis. Here, we present the co-habitation of T. asahii and R. mucilaginosa as causative agents of onychomycosis in a healthy 41-year-old male in China. Direct microscopic examination, fungal culture and MALDI-TOF MS were employed in isolated pathogens; hence, antifungal susceptibility test was evaluated. T. asahii was sensitive to posaconazole, voriconazole and itraconazole, whereas R. mucilaginosa was sensitive to both 5-flucytosine and amphotericin B. This report highlights the co-habitation of T. asahii and R. mucilaginosa in the causation of onychomycosis and to raise the awareness of this infection among dermatologists.

Keywords

Onychomycosis Mixed infection Trichosporon asahii Rhodotorula mucilaginosa Morphology 

Notes

Acknowledgements

We are thankful for the funds provided by Basic Medical College of Chongqing Medical University (Grant No. 4101070003] and Chongqing Research Program of Basic Research and Frontier Technology (No. cstc2015jcyjA10006). We also thank the patient and Professor Xia Yun from Clinical Department, First Affiliated Hospital of Chongqing Medical University, for their technical support of fungi identification.

Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interest.

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© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of Microbiology, College of Basic Medical SciencesChongqing Medical UniversityChongqingChina
  2. 2.Department of Infectious DiseasesThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina

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