Subcutaneous Fungal Infection Caused by a Non-sporulating Strain of Corynespora cassiicola Successfully Treated with Terbinafine
- 4 Downloads
Corynespora cassiicola is a common plant pathogen, but C. cassiicola infection in human hosts is extremely rare. In this report, we present an 84-year-old male with long-term use of inhaled corticosteroids who developed a subcutaneous infection caused by C. cassiicola. The organism was isolated from both wound culture and biopsy specimen from the skin lesion. However, no microscopic diagnostic characters could be obtained because the isolates failed to sporulate on different culture media. Molecular diagnosis by amplification and sequencing of the internal transcribed spacer regions of ribosomal DNA was performed, and the sequences of the isolates were identical to those of C. cassiicola. The patient was treated successfully with oral terbinafine therapy for 12 weeks. In this report, we also review the epidemiology, clinical and therapeutic facets of cutaneous C. cassiicola infection.
KeywordsSubcutaneous infection Mycoses Corynespora cassiicola Terbinafine
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no financial or non-financial conflicts of interest related to the subject matter or materials discussed in this article.
- 2.Deon M. Importance de la cassiicoline en tant qu'effecteur de la Corynespora Leaf Fall (CLF) chez l'hévéa: Développement d'outils pour le contrôle de la maladie. Thèse Université Blaise Pascal (Clermont Ferrand 2) 2012 197 p. 2012.Google Scholar
- 4.De Hoog GS, GJ, Gene JL, Figueras MJ. Atlas of clinical fungi. 2nd ed. Utrecht: Centraalbureau voor Schimmelcultures; 2000.Google Scholar
- 5.Newsam A. Plant Pathology Division Report: Plant Pathology Division Report. Kuala Lumpur, Malaysia: Rubber Research Institute of Malaysia; 1960.Google Scholar
- 6.T. Ramakrishnan PP. Leaf spot of rubber caused by Corynespora cassiicola (Berk. & Curt.) Wei., Rubber Board Bull. 51961.Google Scholar
- 20.Ellis MB, Holliday P. Corynespora cassiicola CMI descriptions of pathogenic. Fungi Bacteria. 1971;303:1.Google Scholar