Persistent hematogenous dissemination in pulmonary P. jiroveci infection

  • E. RighiEmail author
  • A. La Rosa
  • A. Sartor
  • A. Londero
  • A. Carnelutti
  • M. Bassetti
Mycopathologia IMAGES


Pneumocystis jiroveci pneumonia in non-HIV patients is infrequent and characterized by atypical presentations and increased severity. Although hematogenous dissemination from the lungs can lead to extrapulmonary infections, isolation of oocysts from blood in human subjects has not been documented. We report a case of P. jiroveci pneumonia with persistent isolation of oocysts from blood and positivity of P. jiroveci polymerase chain reaction. The patient presented with bilateral diffuse pulmonary nodules and received prolonged treatment with trimethoprim/sulfamethoxazole.


Pneumocystis jiroveci HIV-negative patient Persistent infection Blood oocysts 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from the participant included in the study.

Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Infectious Diseases DivisionSanta Maria della Misericordia University HospitalUdineItaly
  2. 2.Infectious Diseases, Department of Diagnostics and Public HealthUniversity of VeronaVeronaItaly
  3. 3.Microbiology DivisionSanta Maria della Misericordia University HospitalUdineItaly

Personalised recommendations