Subcutaneous Infection Associated with Trichosporon ovoides: A Case Report and Review of Literature
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Abstract
Trichosporon species are opportunistic yeasts which can cause infections, especially in immunocompromised patients. This is a report of Trichosporon ovoides that caused subcutaneous infection in a patient with underlying ischemic heart disease. The identification of fungal isolate was confirmed by PCR sequencing of ITS and large subunit regions in rRNA gene. In vitro susceptibility study showed that the isolate was susceptible to amphotericin B, fluconazole and voriconazole, and resistant to caspofungin, anidulafungin and itraconazole. The lesion improved after treatment with oral fluconazole and topical miconazole.
Keywords
Trichosporon ovoides Trichosporonosis Subcutaneous infectionNotes
Acknowledgments
The authors would like to thank the Director General of Health, Malaysia, and the Director of IMR for permission to publish this article. We would also like to acknowledge the Department of Pathology, Sultanah Bahiyah Hospital, Alor Setar, Kedah, Malaysia, for providing the yeast isolate.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical Standard
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
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