, Volume 180, Issue 3–4, pp 251–255 | Cite as

A Case of Fungus Ball-Type Pansinusitis Due to Fusarium proliferatum

  • Seyed Jamal Hashemi
  • Mojtaba Mohammadi Ardehali
  • Sassan Rezaie
  • Ensieh Zibafar
  • Mohseh Gerami Shoar
  • Ali Rezaei-Matehkolaei
  • Hassan Ehteram
  • Mohammad Javad Najafzadeh
  • Mehdi NazeriEmail author


Incidence of fungal sinusitis due to the genus Fusarium has increased during the last two decades. We report a case of fungus ball sinusitis with multiple sinuses involvement in an Iranian 21-year-old woman. The patient was diagnosed as having a fungus ball-type sinusitis in computed tomography scan. The sinus biopsy revealed fungal structures on histopathological and direct microscopic examinations and a Fusarium species arose in culture. Partial sequencing of the translation elongation factor 1-alpha identified the isolate as F. proliferatum. Removal of all lesions by endoscopic surgery resulted in a favorable outcome. To the best of our knowledge, this is the first case of F. proliferatum-associated fungus ball which involved multi-sinus and highlights the efficiency of molecular methods for discrimination of fungal agents involved.


Fusarium proliferatum Sinusitis Fungus ball TEF-1α 



This research has been funded and supported by Tehran University of Medical sciences (TUMS), Grant No. 12985.

Conflict of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  • Seyed Jamal Hashemi
    • 1
  • Mojtaba Mohammadi Ardehali
    • 2
  • Sassan Rezaie
    • 1
  • Ensieh Zibafar
    • 1
  • Mohseh Gerami Shoar
    • 1
  • Ali Rezaei-Matehkolaei
    • 3
    • 7
  • Hassan Ehteram
    • 4
  • Mohammad Javad Najafzadeh
    • 5
  • Mehdi Nazeri
    • 6
    Email author
  1. 1.Department of Medical Mycology & Parasitology, School of Public HealthTehran University of Medical SciencesTehranIran
  2. 2.Otorhinolaryngology Research Center, Amir Alam Educational HospitalTehran University of Medical SciencesTehranIran
  3. 3.Department of Medical Mycology, School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran
  4. 4.Department of Pathology, School of MedicineKashan University of Medical SciencesKashanIran
  5. 5.Department of Parasitology and Mycology, Ghaem Hospital, School of MedicineMashhad University of Medical SciencesMashhadIran
  6. 6.Department of Medical Mycology & Parasitology, School of MedicineKashan University of Medical SciencesKashanIran
  7. 7.Health Research Institute, Infectious and Tropical Diseases Research CenterAhvaz Jundishapur University of Medical SciencesAhvazIran

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