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Mycopathologia

, Volume 176, Issue 5–6, pp 457–462 | Cite as

Extensive Deep Dermatophytosis Cause by Trichophyton rubrum in a Patient with Liver Cirrhosis and Chronic Renal Failure

  • Lung-Chi Wu
  • Pei-Lun Sun
  • Yun-Ting ChangEmail author
Article

Abstract

Dermatophytes are the main pathogen of superficial skin fungal infections. On rare occasions, they can cause deep and extensive infections, especially in immunocompromised hosts. We reported a 48-year-old patient with liver cirrhosis and chronic renal failure who developed an extensive deep dermatophytosis with possible hematogenous dissemination. Skin histopathology showed extensive involvement of hair follicles and dermis by fungal elements. The pathogen was cultured from both skin biopsy specimen and central venous line. It was identified as Trichophyton rubrum by morphology and further conformed by sequencing of internal transcribed spacers of ribosomal DNA. The patient died quickly before the identification was available.

Keywords

Extensive Deep Dermatophytosis Trichophyton rubrum Liver cirrhosis Chronic renal failure 

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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Department of DermatologyTaipei Veterans General HospitalTaipeiTaiwan
  2. 2.Department of Internal MedicineTaichung Armed Forces General HospitalTaichungTaiwan
  3. 3.National Defense Medical CenterTaipeiTaiwan
  4. 4.Department of DermatologyMackay Memorial HospitalTaipeiTaiwan
  5. 5.Institute of Ecology and Evolutionary BiologyNational Taiwan UniversityTaipeiTaiwan
  6. 6.Department of DermatologyNational Yang-Ming UniversityTaipei 112Taiwan

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