, Volume 175, Issue 3–4, pp 323–330 | Cite as

Pleural Effusion an Unusual Feature of Paracoccidioidomycosis: Report of Two New Cases with a Systematic Review of the Literature

  • Cecília Bittencourt Severo
  • Aline Gehlen Dall Bello
  • Flávio de Mattos Oliveira
  • Luciana Silva Guazzelli
  • Rogério Tregnago
  • Marlene Haas
  • Bruno Hochhegger
  • Luiz Carlos Severo


Paracoccidioidomycosis (PCM) is an endemic disease restricted geographically to Latin America. Brazil accounts for about 80 % of the reported cases, and lungs are most frequently affected. A suggestive radiograph of PCM may only be seen late in the course of the disease. At the beginning, it mimics tuberculosis. On the other hand, pleural effusion on rare occasions has been reported in PCM. For this reason, we report two cases with such uncommon manifestation. Our first patient presented pleural effusion probably caused by PCM (a previously unreported cause of lung mass accompanied by effusion); the second with proved pleural effusion due to PCM. A systematic review of the literature was done.


Paracoccidioidomycosis Paracoccidioides brasiliensis Pleural effusion Systematic review 


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Cecília Bittencourt Severo
    • 1
  • Aline Gehlen Dall Bello
    • 2
  • Flávio de Mattos Oliveira
    • 1
  • Luciana Silva Guazzelli
    • 1
  • Rogério Tregnago
    • 3
  • Marlene Haas
    • 4
  • Bruno Hochhegger
    • 5
  • Luiz Carlos Severo
    • 6
  1. 1.Mycology Laboratory, Hospital Santa RitaIrmandade Santa Casa de Misericórdia de Porto Alegre (ISCMPA)Porto AlegreBrazil
  2. 2.Universidade Federal do Rio Grande do Sul (UFRGS)Porto AlegreBrazil
  3. 3.Hospital TachiniBento GonçalvesBrazil
  4. 4.Irmandade Santa Casa de Misericórdia de Porto Alegre (ISCMPA)Porto AlegreBrazil
  5. 5.Irmandade Santa Casa de Misericórdia de Porto Alegre (ISCMP)Universidade Federal do Rio Grande do Sul (UFRGS)Porto AlegreBrazil
  6. 6.Universidade Federal do Rio Grande do Sul (UFRGS)–Professor associado (nível 04), Pesquisador 1B CNPqPorto AlegreBrazil

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