, Volume 172, Issue 1, pp 73–76 | Cite as

Lack of Candida africana and Candida dubliniensis in Vaginal Candida albicans Isolates in Turkey Using HWP1 Gene Polymorphisms

  • Ramazan Gumral
  • Banu Sancak
  • Ahmet Barış Guzel
  • Mehmet Ali Saraçlı
  • Macit IlkitEmail author


Candida africana differs from the common strains of C. albicans and C. dubliniensis morphologically, physiologically, genetically, and, in particular, clinically. This fungal pathogen is primarily recovered from genital specimens, especially in vaginal specimens. In this investigation, we reexamined 195 vaginal C. albicans isolates for the presence of C. africana and C. dubliniensis by using hyphal wall protein 1 (HWP1) gene polymorphisms. All study isolates were confirmed to be C. albicans, and none were verified as either C. africana or C. dubliniensis. In conclusion, the HWP1 gene polymorphisms offer a useful tool in the discrimination of C. africana, C. albicans, and C. dubliniensis. Further studies may highlight the pathogenesis and importance of this yeast in vulvovaginal candidiasis.


Candida africana Candida albicans Candida dubliniensis Chlamydospore HWP1 gene Vaginitis 



We offer our sincere thanks to the physicians of Çukurova Maternity and Children’s Hospital for their efforts in the provision of clinical samples. We also thank Aygul Turaç-Biçer and Tuba Yuksel for their kind assistance in the laboratory workup.


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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Ramazan Gumral
    • 1
  • Banu Sancak
    • 2
  • Ahmet Barış Guzel
    • 3
  • Mehmet Ali Saraçlı
    • 1
  • Macit Ilkit
    • 4
    Email author
  1. 1.Department of MicrobiologyGulhane Military Medical AcademyAnkaraTurkey
  2. 2.Department of Microbiology, Faculty of MedicineUniversity of HacettepeAnkaraTurkey
  3. 3.Department of Obstetrics and Gynecology, Faculty of MedicineUniversity of ÇukurovaAdanaTurkey
  4. 4.Division of Mycology, Department of Microbiology, Faculty of MedicineUniversity of ÇukurovaAdanaTurkey

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