Mycopathologia

, Volume 166, Issue 3, pp 159–162

Lymphocutaneous Sporotrichosis in an Immunocompetent Patient: A Case Report from Extreme Southern Italy

  • Giuseppe Criseo
  • Giovanna Malara
  • Orazio Romeo
  • Antonio Puglisi Guerra
Article

Abstract

Sporotrichosis is a mycotic infection rarely encountered in European countries, including Italy. We describe lymphocutaneous sporotrichosis in an immunocompetent 64-year-old male Italian mason. The patient had linear nodules along the right upper arm with severe lymphadenopathy in the same arm. Sporothrix schenckii was identified by phenotypic and molecular methods. Treatment with itraconazole and methylprednisolone followed by administration of itraconazole alone successfully cured the infection. To our knowledge, this is the first documented report of sporotrichosis from Calabria and Sicily, extreme southern Italy.

Keywords

Lymphocutaneous Sporotrichosis Sporothrix schenckii Sporotrichosis in Italy Itraconazole 

References

  1. 1.
    Lopes-Bezerra LM, Schubach A, Costa RO. Sporothrix schenckii and sporotrichosis. An Acad Bras Cienc. 2006;78:293–308.PubMedGoogle Scholar
  2. 2.
    De Araujo T, Marques AC, Kerdel F. Sporotrichosis. Int J Dermatol. 2001;40:737–742.PubMedCrossRefGoogle Scholar
  3. 3.
    Schubach TM, de Oliveira Schubach A, dos Reis RS, Cuzzi-Maya T, Blanco TC, Monteiro DF, Barros BM, Brustein R, Zancopé-Oliveira RM, Fialho Monteiro PC, Wanke B. Sporothrix schenckii isolated from domestic cats with and without sporotrichosis in Rio de Janeiro, Brazil. Mycopathologia. 2002;153:83–6.PubMedCrossRefGoogle Scholar
  4. 4.
    Cafarchia C, Sasanelli M, Lia RP, de Caprariis D, Guillot J, Otranto D. Lymphocutaneous and nasal sporotrichosis in a dog from southern Italy: case report. Mycopathologia. 2007;163:75–9.PubMedCrossRefGoogle Scholar
  5. 5.
    Ramos-e-Silva M, Vasconcelos C, Carneiro S, Cestari T. Sporotrichosis. Clin Dermatol. 2007;25:181–7.PubMedCrossRefGoogle Scholar
  6. 6.
    Ishizaki H, Kawasaki M, Aoki M, Matsumoto T, Padhye AA, Mendoza M, Negroni R. Mitochondrial DNA analysis of Sporothrix schenckii in North and South America. Mycopathologia. 1998;142:115–8.PubMedCrossRefGoogle Scholar
  7. 7.
    Vismer HF, Hull PR. Prevalence, epidemiology and geographical distribution of Sporothrix schenckii infections in Gauteng, South Africa. Mycopathologia. 1997;137:137–43.PubMedCrossRefGoogle Scholar
  8. 8.
    Feeney KT, Arthur IH, Whittle AJ, Altman SA, Speers DJ. Outbreak of sporotrichosis, Western Australia. Emerg Infect Dis. 2007;13:1228–31.PubMedGoogle Scholar
  9. 9.
    Devi KR, Devi MU, Singh TN, Devi KS, Sharma SS, Singh LR, Singh HL, Singh NB. Emergence of sporotrichosis in Manipur. Indian J Med Microbiol. 2006;24:216–9.PubMedGoogle Scholar
  10. 10.
    Barile F, Mastrolonardo M, Loconsole F, Rantuccio F. Cutaneous sporotrichosis in the period 1978–1992 in the province of Bari, Apulia, Southern Italy. Mycoses. 1993;36:181–5.PubMedGoogle Scholar
  11. 11.
    Alberici F, Paties CT, Lombardi G, Ajello L, Kaufman L, Chandler F. Sporothrix schenckii var luriei as the cause of sporotrichosis in Italy. Eur J Epidemiol. 1989;5:173–7.PubMedCrossRefGoogle Scholar
  12. 12.
    Baroni A, Palla M, Iovene MR, Faccenda F, Aiello FS, Puca RV, Satriano RA. Sporotrichosis: success of itraconazole treatment. Skinmed. 2007;6:41–44.PubMedCrossRefGoogle Scholar
  13. 13.
    Travassos LR, Lloyd KO. Sporothrix schenckii and related species of Ceratocystis. Microbiol Rev. 1980;44:683–721.PubMedGoogle Scholar
  14. 14.
    Kano R, Nakamura Y, Watanabe S, Tsujimoto H, Hasegawa A. Identification of Sporothrix schenckii based on sequences of the chitin synthase 1 gene. Mycoses. 2001;44:261–5.PubMedCrossRefGoogle Scholar
  15. 15.
    Kohler LM, Soares BM, de Assis Santos D, Da Silva Barros ME, Hamdan JS. In vitro susceptibility of isolates of Sporothrix schenckii to amphotericin B, itraconazole, and terbinafine: comparison of yeast and mycelial forms. Can J Microbiol. 2006;52:843–7.PubMedCrossRefGoogle Scholar
  16. 16.
    Ishizaki H, Kawasaki M, Aoki M, Wu S, Lin J, Kim JA, Won YH, Calvo CR. Mitochondrial DNA analysis of Sporothrix schenckii from China, Korea and Spain. Jpn J Med Mycol. 2004;45:23–5.Google Scholar
  17. 17.
    Bonifaz A, Fierro L, Saúl A, Ponce RM. Cutaneous sporotrichosis. Intermittent treatment (pulses) with itraconazole. Eur J Dermatol. 2008;18:61–4.PubMedGoogle Scholar
  18. 18.
    Sharkey-Mathis PK, Kauffman CA, Graybill JR, Stevens DA, Hostetler JS, Cloud G, Dismukes WE. Treatment of sporotrichosis with itraconazole. Am J Med. 1993;95:279–85.PubMedCrossRefGoogle Scholar
  19. 19.
    Tay YK, Goh CL, Ong BH. Sporotrichosis: a case report and successful treatment with itraconazole. Cutis. 1997;60:87–90.PubMedGoogle Scholar
  20. 20.
    Kauffman CA, Bustamante B, Chapman SW, Pappas PG. Clinical practice guidelines for the management of sporotrichosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis. 2007;45:1255–65.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Giuseppe Criseo
    • 1
  • Giovanna Malara
    • 2
  • Orazio Romeo
    • 1
  • Antonio Puglisi Guerra
    • 2
  1. 1.Department of MicrobiologicalGenetic and Molecular Sciences University of MessinaMessinaItaly
  2. 2.Department of DermatologyPapardo HospitalMessinaItaly

Personalised recommendations