Plant stem cells: what we know and what is anticipated
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Plant stem cell research is of interest due to stem cells ability of unlimited division, therapeutic potential and steady supply to provide precursor cells. Their isolation and culture provides the important source for the production of homogenous lines of active constituents that allow large-scale production of various metabolites. The process of dedifferentiation and reversal to pluripotent cells involves the various pathways genes related to the stem cells and are associated to each other for maintaining a specific niche. Domains such as niche dynamics and maintenance signaling can be used for the identification of genes for stem cell niche. Significant findings have been achieved in the past on plant stem cells however our understanding towards mechanisms underlying some specific phenomenon like dedifferentiation, regulation, niche dynamics is still in infancy. The present review is based on the past research efforts and also pave a way forward for the future anticipation in the field of development of cell cultures for the production of active metabolites on large scale and undertanding transcriptional regulation of stem cell genes involved in niche signaling.
KeywordsDedifferentiation DNA damage Genes Niche Plant stem cells Pluripotent
The authors acknowledge the Council of Scientific and Industrial Research (CSIR), Government of India, under the project “Physiological, biochemical and molecular analysis of economically important plants for understanding and exploiting their growth, adaptation and metabolic mechanisms (MLP-0071)” for financial support. The authors are thankful to Director, CSIR-IHBT for providing necessary facilities.
ARW—Conceived the concept, ARW & AS—Framed the design, ARW, KT & AS—Manuscript written and edition. All authors read and approved the final manuscript.
Compliance with ethical standards
Conflict of interest
The authors declare that there is no conflict of interest.
Review article in accordance with ethical standard of institution.
- 7.Morus M, Baran M, Rost-Roszkowska M, Skotnicka-Graca U (2014) Plant stem cells as innovation in cosmetics. Acta Pol Pharm 71:701–707Google Scholar
- 16.Zhu J (2017) Plant stem cell and its pluripotency. Int J Stem Cell Res 3(1):001–006Google Scholar
- 26.Boutilier K, Offringa R, Sharma VK, Kieft H, Ouellet T, Zhang L, Hattori J, Liu CM, Van Lammeren Andre AM, Miki Brian LA, Custers Jan BM, Van Lookeren Campagne Michiel M (2002) Ectopic expression of BABY BOOM triggers a conversion from vegetative to embryonic growth. Plant Cell 14:1737–1749PubMedPubMedCentralGoogle Scholar
- 27.Ivanov VB (1986) Specific features of cell proliferation in plants with reference to the problem of stem cells. Tsitologiya 28:295–302Google Scholar
- 29.Barlow PW (1997) Stem cells and founder zones in plants, particularly their roots. In: Poten CS (ed) Stem cells. Academic, London, pp 29–57Google Scholar
- 30.Francis D (1997) The stem cell concept applied to shoot meristems of higher plants. In: Poten CS (ed) Stem cells. Academic, London, pp 59–73Google Scholar
- 33.Vagi P, Preininger E, Kovacs GM, Kristof Z, Boka K, Boddi B (2013) Structure of plants and fungi. In: Kristof Z (ed) Eötvös Loránd University, pp. 1–109Google Scholar
- 37.Klekowski E (2003) Plant clonality, mutation, diplontic selection and mutational meltdown. Biol J Linn Soc 79:61–67Google Scholar
- 43.Liu HL, Wang GC, Feng Z, Zhu J (2010) Screening of genes associated with dedifferentiation and effect of LBD29 on pericycle cells in Arabidopsis thaliana. Plant Growth Regul 62:127–136Google Scholar
- 51.Zhou C, Guo J, Feng Z, Cui X, Zhu J (2012) Molecular characterization of a novel AP2 transcription factor ThWIND1-L from Thellungiella halophila. Plant Cell Tiss Org 110:423–433Google Scholar
- 53.Li F, Cui X, Feng Z, Du X, Zhu J (2012) The effect of 2,4-D and kinetin on differentiation of petiole cells in Arabidopsis thaliana. Biol Plantarum 56:121–125Google Scholar
- 54.Ito Y, Nakanomyo I, Motose H, Iwamoto K, Sawa S, Dohmae N, Fakuda H (2006) Dodeca-CLE peptides as suppressors of plant stem differentiation. Science 313:8842–8845Google Scholar
- 56.Cai S, Fu XB, Sheng ZY (2007) Dedifferentiation: a new approach in stem cell research. Bioscience 57:655–662Google Scholar
- 61.Yadav RK, Perales M, Gruel J, Ohno C, Heisler M et al (2013) Plant stem cell maintenance involves direct transcriptional repression of differentiation program. Mol Syst Biol 9:1–13Google Scholar
- 77.Desvoyes B, Sanchez MP, Ramirez-Parra E, Gutierrez C (2010) Impact of nucleosome dynamics and histone modifications on cell proliferation during Arabidopsis development. Heredity (Edinb.) 105:80–91Google Scholar
- 79.Ochoa-Villarreal M, Howat S, Jang MO, Kim IS, Jin Y-W, Lee E-K, et al (2015) Cambial meristematic cells: a platform for the production of plant natural products. New Biotechnol 32(6):581–587Google Scholar
- 80.Jang SH, Yu JY, Lee EK, Lim MJ, Hong NJ, Oh IS, Kang TH, So EM, Jin YW, Jin YS, Jeong YS, Jeong HS, Lee JC, Jang YS (2012) In vitro anti-oxidant and anti-inflammatory activities of cambial meristematic cells established from Ginkgo biloba L. J Med Plants Res 6:3048–3058Google Scholar
- 81.http://www.ulprospector.com/. Accessed 21 Aug 2018
- 85.Barbulova A, Fabio A, Gabriella C (2014) Plant cell cultures as source of cosmetic active ingredients. Cosmetics 1(2):94–104Google Scholar