Trends to store digital data in DNA: an overview
There has been an ascending growth in the capacity of information being generated. The increased production of data in turn has put forward other challenges as well thus, and there is the need to store this information and not only to store it but also to retain it for a prolonged time period. The reliance on DNA as a dense storage medium with high storage capacity and its ability to withstand extreme environmental conditions has increased over the past few years. There have been developments in reading and writing different forms of data on DNA, codes for encrypting data and using DNA as a way of secret writing leading towards new styles like stenography and cryptography. The article outlines different methods adopted for storing digital data on DNA with pros and cons of each method that has been applied plus the advantages and limitations of using DNA as a storage medium.
KeywordsAlignment Cryptography Digital data Oligonucleotides Sequencing
This work is carried out with the help of prestigious material of the libraries and special thanks to Institute of Industrial Biotechnology, Government College University, Lahore.
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Conflict of interest
The authors declare that they have no conflict of interest.
The authors assure the integrity and quality of our research work. It is also stated that there is no plagiarism in this work and all points taken from other authors are well cited in the text. This study is completely independent and impartial.
Research involving human participants and/or animals
This article does not contain any studies conducted on human or animal subjects.
- 2.Hakami HA, Chaczko Z, Kale A (2015) Review of big data storage based on DNA computing. In: Proceedings of the Asia-Pacific Conference on Computer-Aided System Engineering (APCASE’15), Quito Ecuador, pp 113–117Google Scholar
- 5.Borda M, Tornea O (2010) DNA secret writing techniques. In: Proceedings of the 8th International Conference on Communications (COMM’10). Bucharest, Romania, pp 451–456Google Scholar
- 7.DeSilva PY, Ganegoda GU (2016) New trends of digital data storage in DNA. Biomed Res Int 8072463:14Google Scholar
- 8.Kac E (1999) “Genesis-art of DNA,” http://www.ekac.org/geninfo
- 15.Cui G, Li C, Li H, Li X (2009) dna computing and its application to information security field. In: Proceedings of the 5th International Conference of Natural Computation, Tianjian, China; IEEE, pp 14–16Google Scholar
- 16.Ning K (2009) A pseudo DNA Cryptography method. http://arxiv.org/abs/0903.269
- 24.Cosemans S, Dehaene W, Catthoor F (2008) A 3.6 pJ/access 480 MHz, 128Kbit on-Chip SRAM with 850 MHz boost mode in 90 nm CMOS with tunable sense amplifiers to cope with variability. In Solid-State Circuits Conference, 2008. ESSCIRC 2008. 34th European IEEE, pp 278–281Google Scholar
- 26.Sangwan N (2012) Text encryption with huffman compression. Int J Comput Appl 54:29–32Google Scholar
- 27.Zhang Y, Bochen Fu LH (2012) Research on DNA cryptography. In: Sen J (ed) Applied cryptography and network security. pp 357–376, InTech, Rijeka, Croatia, http://www.intechopen.com/books/applied-cryptography-and-networksecurity/ research-on-dna-cryptography
- 29.Borda ME, Tornea O, Hodorogea T (2009) Secret writing by DNA hybridization. Acta Technica Napocensis Electron Telecommun 50:21–24Google Scholar
- 32.Schuster SC (2008) Next-generation sequencing transforms today’s biology. Nature 5:16–18Google Scholar
- 40.Ravinderjit SB (2001) Solution of a satisfiability problem on a gel-based DNA computer. DNA computing. Springer, Berlin, pp 27–42Google Scholar
- 41.Macdonald J, Stefanovic D, Stojanovic M (2009) Des assemblages d’ADN rompus au jeu et au travail, Pour la Science, pp 68–75Google Scholar
- 42.Nayebi A (2009) Fast matrix multiplication techniques based on the Adleman-Lipton model, arXiv: 0912.0750Google Scholar
- 50.Milenkovic O, Kashyap N (2006) On the design of codes for DNA computing. In coding and cryptography. Springer, New York, pp 100–119Google Scholar