Molecular Biology Reports

, Volume 41, Issue 2, pp 599–611 | Cite as

Pathogenesis related-10 proteins are small, structurally similar but with diverse role in stress signaling

  • Parinita Agarwal
  • Pradeep K. Agarwal


Pathogenesis related-10 proteins are small proteins with cytosolic localization, conserved three dimensional structures and single intron at 185 bp position. These proteins have a broad spectrum of roles significantly in biotic and abiotic stresses. The RNase activity, ligand binding activity, posttranslational modification (phosphorylation) and phytohormone signaling provide some information into the mechanism of the regulation of PR-10 proteins, however the presence of isoforms makes it difficult to decipher its exact mode of function. The involvement of phosphorylation/dephosphorylation events in its activation is interesting and provides unique and unbiased insights into the complexity of its regulation. Studies on upstream region of different PR-10 genes indicate the presence of cis-acting elements for WRKY, RAVI, bZ1P, ERF, SEBF and Pti4 transcription factors indicating their role in regulating PR-10 promoter. In this review, we discuss in detail the structure and mechanism of regulation of PR-10 proteins.


Abiotic Biotic Ligand binding Pathogenesis related proteins Phosphorylation Promoter RNase activity 



Abscisic acid


1-Aminocyclopropane-1-carboxylic acid


Cytokinin-specific binding protein




Effector triggered immunity


Hypersensitive response




Intracellular pathogenesis-related proteins


Jasmonic acid


Lipid transfer proteins


Methyl jasmonate


(S)-Norcoclaurine synthases


Nuclear localization signal


Pathogen associated molecular patterns


Pathogenesis related-10 proteins


PAMP triggered immunity


Post translational modification


Reactive oxygen species


Salicylic acid


Systemic acquired resistance


Silencer element binding factor


Transcription factor


Thaumatin-like proteins


Tobacco mosaic virus



The financial assistance from CSIR is duly acknowledged.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  1. 1.Discipline of Wasteland ResearchCSIR-Central Salt & Marine Chemicals Research InstituteBhavnagarIndia

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