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Molecular Biology Reports

, Volume 39, Issue 12, pp 10265–10271 | Cite as

Genetic data provided by 21 autosomal STR loci from Chinese Tujia ethnic group

  • Guo-lian YuanEmail author
  • Chun-mei Shen
  • Hong-dan Wang
  • Wen-juan Liu
  • Guang Yang
  • Jiang-wei Yan
  • Hai-Xia Qin
  • Tong Xie
  • Hangyan Ran
  • Jie Yuan
  • Zuochun Liu
  • Bofeng Zhu
Article

Abstract

The aim of this study was to investigate allelic frequency distribution and forensic genetic parameters of autosomal short tandem repeats (STR) loci of the population samples from 107 Tujia individuals from Chinese Hubei Province. Twenty-one autosomal STR genetic markers (D9S1122, D6S474, D6S1017, D5S2500, D4S2408, D3S4529, D2S441, D2S1776, D22S1045, D20S482, D1S1677, D1S1627, D1GATA113, D19S433, D18S853, D17S1301, D11S4463, D12ATA63, D10S1248, D10S1435 and D14S1434) were simultaneously amplified in a new multiplex polymerase chain reaction system. 155 alleles for all the STR loci from the Tujia population were observed and the corresponding allelic frequencies ranged from 0.005 to 0.589. Expected heterozygosity, polymorphic information content, power of discrimination and power of exclusion of the 21 STR loci in the Tujia population were from 0.579 to 0.824, from 0.525 to 0.802, from 0.773 to 0.945 and from 0.257 to 0.641, respectively. Our results indicate that the autosomal STRs multiplex system provides highly informative STR data and could be useful in forensic individual identification and parentage testing in this region.

Keywords

Short tandem repeat Chinese Tujia ethnic group Allelic diversity 

Notes

Acknowledgments

This project was supported by the National Natural Science Foundation of China (NSFC, No. 31271348), the Program for New Century Excellent Talents of the Ministry of Education, China (NECT-10-0687); supported by the Fundamental Research Funds for the Central University, China (2011jdgz20); and the Shaan’xi Provincial Science and Technology Research and Development Project Fund (No. 2012K16-08-01), China.

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Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  • Guo-lian Yuan
    • 1
    • 2
    Email author
  • Chun-mei Shen
    • 3
  • Hong-dan Wang
    • 4
    • 5
  • Wen-juan Liu
    • 5
  • Guang Yang
    • 6
  • Jiang-wei Yan
    • 7
  • Hai-Xia Qin
    • 8
  • Tong Xie
    • 9
  • Hangyan Ran
    • 10
  • Jie Yuan
    • 10
  • Zuochun Liu
    • 10
  • Bofeng Zhu
    • 2
  1. 1.Scientific Research and Experiment Center, The Second Affiliated Hospital, School of MedicineXi’an Jiaotong UniversityXi’anPeople’s Republic of China
  2. 2.The Key Laboratory of Environment and Gene Related to Diseases (Xi’an Jiaotong University), Ministry of EducationXi’anPeople’s Republic of China
  3. 3.Blood Center of the Shaanxi ProvinceShaanxiPeople’s Republic of China
  4. 4.Medical Genetic Institute of Henan ProvincePeople’s Hospital of Henan ProvinceZhengzhouPeople’s Republic of China
  5. 5.School of MedicineXi’an Jiaotong UniversityXi’anPeople’s Republic of China
  6. 6.Vascular Biology CenterGeorgia Health Sciences UniversityAugustaUSA
  7. 7.Beijing Institute of GenomicsChinese Academy of ScienceBeijingPeople’s Republic of China
  8. 8.Department of Internal MedicineMorehouse School of MedicineAtlantaUSA
  9. 9.School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhouPeople’s Republic of China
  10. 10.Affiliated Hospital of Hubei Institute for NationalitiesEnshiPeople’s Republic of China

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