Molecular Biology Reports

, Volume 38, Issue 3, pp 2151–2154 | Cite as

Novel single nucleotide polymorphism identification in interleukin-6 gene of Pakistani sheep

  • Safdar Ali
  • Masroor Ellahi Babar
  • A. Hossain Farid
  • Pervez Akhtar
  • Ali Raza AwanEmail author


The present study aimed to identify single-nucleotide polymorphism (SNP) in coding and non-coding regions of interleukin-6 (IL-6) gene of Pakistani sheep. The IL-6 gene of 205 animals from nine sheep breeds were sequenced for screening of SNP. Characterizing the IL-6 gene revealed thirteen SNP sites within the intronic region of IL-6 gene. The novel SNPs found in the present study can serve as genetic marker for association studies with susceptibility/resistance to parasite infection in sheep. This is first report of SNP polymorphism of IL-6 gene of Pakistani sheep.


Sheep Polymorphism SNP Pakistan Interleukin Ovine 


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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Safdar Ali
    • 1
  • Masroor Ellahi Babar
    • 2
  • A. Hossain Farid
    • 3
  • Pervez Akhtar
    • 1
  • Ali Raza Awan
    • 2
    Email author
  1. 1.Department of Animal Breeding and GeneticsUniversity of Agriculture FaisalabadFaisalabadPakistan
  2. 2.Institute of Biochemistry & BiotechnologyUniversity of Veterinary and Animal SciencesLahorePakistan
  3. 3.Department of Agriculture and Animal SciencesNova Scotia Agricultural CollegeTruroCanada

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