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Motivation and Emotion

, Volume 42, Issue 4, pp 546–554 | Cite as

Dynamic measures of anxiety-related threat bias: Links to stress reactivity

  • Laura J. Egan
  • Tracy A. Dennis-Tiwary
Original Paper

Abstract

Exaggerated attention to threatening information, or the threat bias, has been implicated in the development and maintenance of anxiety disorders. Recent research has highlighted methodological limitations in threat bias measures, such as temporal insensitivity, leading to the development of novel metrics that capture change and variability in threat bias over time. These metrics, however, have rarely been examined in non-clinical samples. The present study aimed to explore the utility of these trial-level metrics in predicting anxiety-related stress reactivity (stress-induced negative mood state) in trait anxious adults (N = 52). Following a stressor, participants completed the dot probe task to generate threat bias scores. Stress reactivity was measured via stress-induced changes in subjective mood state. More variability in trial-level bias scores (TL-BSs) and greater bias away from threat (both mean and peak negative TL-BSs) predicted increased stress reactivity. The temporal characteristics of threat bias and implications for clinically-relevant measurement are discussed.

Keywords

Anxiety Threat bias Trial-level bias score Stress reactivity 

Notes

Disclaimer

The contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIMHD or the NIH.

Funding

This research was made possible by grant SC1MH104907 awarded to TDT from the National Institute of General Medical Sciences and grant R56MH111700 awarded to TDT from the National Institute of Mental Health, both of the National Institutes of Health. This research was also made possible by grant TR000457 of the National Center for Advancing Translational Sciences of the National Institutes of Health.

References

  1. Bardeen, J. R., Daniel, T. A., Hinnant, J. B., & Orcutt, H. K. (2017). Emotion dysregulation and threat-related attention bias variability. Motivation and Emotion.  https://doi.org/10.1007/s11031-017-9604-z.Google Scholar
  2. Bar-Haim, Y., Holoshitz, Y., Eldar, S., Frenkel, T. I., Muller, D., Charney, D. S., et al. (2010). Life-threatening danger and suppression of attention bias to threat. American Journal of Psychiatry, 167, 694–698.  https://doi.org/10.1176/appi.ajp.2009.09070956.CrossRefPubMedGoogle Scholar
  3. Bar-Haim, Y., Lamy, D., Pergamin, L., Bakermans-Kranenburg, M. J., & van IJzendoorn, M. H. (2007). Threat-related attentional bias in anxious and nonanxious individuals: A meta-analytic study. Psychological Bulletin, 133(1), 1–24.  https://doi.org/10.1037/0033-2909.133.1.1.CrossRefPubMedGoogle Scholar
  4. Beck, A. T. (1987). Cognitive models of depression. Journal of Cognitive Psychotherapy, 1, 5–38.Google Scholar
  5. Bradley, B. P., Mogg, K., & Millar, N. H. (2000). Covert and overt orienting of attention to emotional faces in anxiety. Cognition and Emotion, 14(6), 789–808.CrossRefGoogle Scholar
  6. Brown, H. M., Eley, T. C., Broeren, S., MacLeod, C., Rinck, M., Hadwin, J. A., & Lester, K. J. (2014). Psychometric properties of reaction time based experimental paradigms measuring anxiety-related information-processing biases in children. Journal of Anxiety Disorders, 28, 97–107.  https://doi.org/10.1016/j.janxdis.2013.11.004.CrossRefPubMedGoogle Scholar
  7. Carlson, J. M., & Reinke, K. S. (2008). Masked fearful faces modulate the orienting of covert spatial attention. Emotion, 8(4), 522–529.  https://doi.org/10.1037/a0012653.CrossRefPubMedGoogle Scholar
  8. Cisler, J. M., Bacon, A. K., & Williams, N. L. (2009). Phenomenological characteristics of attentional biases towards threat: A critical review. Cognitive Therapy and Research, 33, 221–234.  https://doi.org/10.1007/s10608-007-9161-y.CrossRefPubMedPubMedCentralGoogle Scholar
  9. Cisler, J. M., & Koster, E. H. W. (2010). Mechanisms of attentional biases towards threat in anxiety disorders: An integrative review. Clinical Psychology Review, 30, 203–216.  https://doi.org/10.1016/j.cpr.2009.11.003.CrossRefPubMedGoogle Scholar
  10. Clarke, P. J. F., MacLeod, C., & Shirazee, N. (2008). Prepared for the worst: Readiness to aquire threat bias and susceptibility to elevate trait anxiety. Emotion, 8(1), 47–57.  https://doi.org/10.1037/1528-3542.8.1.47.CrossRefPubMedGoogle Scholar
  11. Davis, M. L., Rosenfield, D., Bernstein, A., Zvielli, A., Reinecke, A., Beevers, C. G., et al. (2016). Attention bias dynamics and symptom severity during and following CBT for social anxiety disorder. Journal of Consulting and Clinical Psychology, 84(9), 795–802.CrossRefPubMedGoogle Scholar
  12. Eldar, S., & Bar-Haim, Y. (2010). Neural plasticity in response to attention training in anxiety. Psychological Medicine, 40, 667–677.  https://doi.org/10.1017/S0033291709990766. doi.CrossRefPubMedGoogle Scholar
  13. Eldar, S., Ricon, T., & Bar-Haim, Y. (2008). Plasticity in attention: Implications for stress response in children. Behaviour Research and Therapy, 46, 450–461.  https://doi.org/10.1016/j.brat.2008.01.012.CrossRefPubMedGoogle Scholar
  14. Eldar, S., Yankelevitch, R., Lamy, D., & Bar-Haim, Y. (2010). Enhanced neural reactivity and selective attention to threat in anxiety. Biological Psychology, 85, 252–257.  https://doi.org/10.1016/j.biopsycho.2010.07.010.CrossRefPubMedGoogle Scholar
  15. Eysenck, M. W. (1992). Anxiety: The cognitive perspective. Hillsdale, NJ: Erlbaum.Google Scholar
  16. Hofmann, S. G. (2007). Cognitive factors that maintain social anxiety disorder: A comprehensive model and its treatment implications. Cognitive Behaviour Therapy, 36(4), 193–209.  https://doi.org/10.1080/16506070701421313.CrossRefPubMedPubMedCentralGoogle Scholar
  17. Iacoviello, B. M., Wu, G., Abend, R., Murrough, J. W., Feder, A., Fruchter, E., et al. (2014). Attention bias variability and symptoms of posttraumatic stress disorder. Journal of Traumatic Stress, 27(2), 1–8.  https://doi.org/10.1002/jts.21899.CrossRefGoogle Scholar
  18. Kirschbaum, C., Pirke, K., & Hellhammer, D. H. (1993). The ‘Trier Social Stress Test’: A tool for investigating psychobiological stress responses in a laboratory setting. Neuropsychobiology, 28, 76–81.CrossRefPubMedGoogle Scholar
  19. Klumpp, H., & Amir, N. (2009). Examination of vigilance and disengagement of threat in social anxiety with a probe detection task. Anxiety, Stress & Coping, 22(3), 283–296.  https://doi.org/10.1080/10615800802449602.CrossRefGoogle Scholar
  20. Koster, E. H. W., Crombez, G., Verschuere, B., & De Houwer, J. (2004). Selective attention to threat in the dot probe paradigm: Differentiating vigilance and difficulty to disengage. Behaviour Research and Therapy, 42, 1183–1192.  https://doi.org/10.1016/j.brat.2003.08.001.CrossRefPubMedGoogle Scholar
  21. Koster, E. H. W., Crombez, G., Verschuere, B., & De Houwer, J. (2006). Attention to threat in anxiety-prone individuals: Mechanisms underlying attentional bias. Cognitive Therapy and Research, 30, 635–643.  https://doi.org/10.1007/s10608-006-9042-9.CrossRefGoogle Scholar
  22. Koster, E. H. W., Crombez, G., Verschuere, B., Van Damme, S., & Wiersema, J. R. (2006). Components of attentional bias to threat in high trait anxiety: Facilitated engagement, impaired disengagement, and attentional avoidance. Behaviour Research and Therapy, 44, 1757–1771.  https://doi.org/10.1016/j.brat.2005.12.011.CrossRefPubMedGoogle Scholar
  23. Koster, E. H. W., Verschuere, B., Crombez, G., & Van Damme, S. (2005). Time-course of attention for threatening pictures in high and low trait anxiety. Behaviour Research and Therapy, 43, 1087–1098.  https://doi.org/10.1016/j.brat.2004.08.004.CrossRefPubMedGoogle Scholar
  24. Lang, P., Bradley, M., & Cuthbert, B. (2008). International affective picture system (IAPS): Affective ratings of pictures and instruction manual (Rep. No. A-8). Technical Report A-8.Google Scholar
  25. LeDoux, J. (1996). The emotional brain. New York: Simon & Schuster.Google Scholar
  26. Lee, J. K., Orsillo, S. M., Roemer, L., & Allen, L. B. (2010). Distress and avoidance in generalized anxiety disorder: Exploring the relationships with intolerance of uncertainty and worry. Cognitive Behaviour Therapy, 39(2), 126–136.  https://doi.org/10.1080/16506070902966918.CrossRefPubMedPubMedCentralGoogle Scholar
  27. MacLeod, C., Campbell, E., Rutherford, L., & Wilson, E. (2004). The causal status of anxiety-linked attentional and interpretive bias. In J. Yiend (Ed.), Cognition, emotion and psychopathology: Theoretical, empirical and clinical directions (pp. 172–189). New York: Cambridge University Press.CrossRefGoogle Scholar
  28. MacLeod, C., Mathews, A., & Tata, P. (1986). Attentional bias in emotional disorders. Journal of Abnormal Psychology, 95, 15–20.  https://doi.org/10.1037/0021-843X.95.1.15.CrossRefPubMedGoogle Scholar
  29. MacLeod, C., Rutherford, E., Campbell, L., Ebsworthy, G., & Holker, L. (2002). Selective attention and emotional vulnerability: Assessing the causal basis of their association through the experimental manipulation of attentional bias. Journal of Abnormal Psychology, 111(1), 107–123.  https://doi.org/10.1037//0021-843X.111.1.107.CrossRefPubMedGoogle Scholar
  30. Mathews, A., & Mackintosh, B. (1998). A cognitive model of selective processing in anxiety. Cognitive Therapy and Research, 22(6), 539–560.  https://doi.org/10.1023/A:1018738019346.CrossRefGoogle Scholar
  31. Mathews, A., Mackintosh, B., & Fulcher, E. P. (1997). Cognitive biases in anxiety and attention to threat. Trends in Cognitive Science, 1(9), 340–345.  https://doi.org/10.1016/S1364-6613(97)01092-9.CrossRefGoogle Scholar
  32. McNair, D. M., Lorr, M., Heuchert, J. W. P., & Droppleman, L. F. (2003). Profile of mood states: Standard form. North Tonawanda, NY: Multi-Health Systems (MHS).Google Scholar
  33. Mogg, K., Bradley, B. P., Miles, F., & Dixon, R. (2004). Time course of attentional bias for threat information in non-clinical anxiety. Behaviour Research and Therapy, 35, 689–700.CrossRefGoogle Scholar
  34. Monk, C. S., Nelson, E. E., McClure, E. B., Mogg, K., Bradley, B. P., Leibenluft, E., et al. (2006). Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. American Journal of Psychiatry, 163(6), 1091–1097.  https://doi.org/10.1176/appi.ajp.163.6.1091.CrossRefPubMedGoogle Scholar
  35. Ouimet, A. J., Gawronski, B., & Dozois, D. J. A. (2009). Cognitive vulnerability to anxiety: A review and integrative model. Clinical Psychology Review, 29, 459–470.  https://doi.org/10.1016/j.cpr.2009.05.004.CrossRefPubMedGoogle Scholar
  36. Price, R. B., Kuckertz, J. M., Siegle, G. J., Ladouceur, C. D., Silk, J. S., Ryan, N. D., et al. (2015). Empirical recommendations for improving the stability of the dot-probe task in clinical research. Psychological Assessment, 27(2), 365–376.  https://doi.org/10.1037/pas0000036.CrossRefPubMedGoogle Scholar
  37. Puliafico, A. C., & Kendall, P. C. (2006). Threat-related attentional bias in anxious youth: A review. Clinical Child and Family Psychology Review, 9(3–4), 162–180.  https://doi.org/10.1007/s10567-006-0009-x.CrossRefPubMedGoogle Scholar
  38. Rodebaugh, T. L., Scullin, R. C., Langer, J. K., Dixon, D. J., Juppert, J. D., Bernstein, A., Zvielli, A., et al. (2016). Unreliability as a threat to understanding psychopathology: The cautionary tale of attentional bias. Journal of Abnormal Psychology, 125(6), 840–851.  https://doi.org/10.1037/abn0000184.CrossRefPubMedPubMedCentralGoogle Scholar
  39. Roy, A. K., Dennis, T. A., & Warner, C. M. (2015). A critical review of attentional threat bias and its role in the treatment of pediatric anxiety disorders. Journal of Cognitive Psychotherapy: An International Quarterly, 29(3), 171–184.  https://doi.org/10.1891/0889-8391.29.3.171.CrossRefGoogle Scholar
  40. Salemink, E., van den Hout, M. A., & Kindt, M. (2007). Selective attention and threat: Quick orienting versus slow disengagement and two versions of the dot probe task. Behaviour Research and Therapy, 45, 607–615.  https://doi.org/10.1016/j.brat.2006.04.004.CrossRefPubMedGoogle Scholar
  41. Salum, G. A., Mogg, K., Bradley, B. P., Gadelha, A., Pan, P., Tamanaha, A. C., et al. (2013). Threat bias in attention orienting: Evidence of specificity in a large community-based study. Psychological Medicine, 43(4), 733–745.  https://doi.org/10.1017/S0033291712001651.CrossRefPubMedGoogle Scholar
  42. Schmukle, S. C. (2005). Unreliability of the dot probe task. European Journal of Personality, 19(7), 595–605.  https://doi.org/10.1002/per.554.CrossRefGoogle Scholar
  43. Sipos, M. L., Bar-Haim, Y., Abend, R., Adler, A. B., & Bliese, P. D. (2013). Postdeployment threat-related attention bias interacts with combat exposure to account for PTSD and anxiety symptoms in soldiers. Depression and Anxiety.  https://doi.org/10.1002/da.22157.PubMedGoogle Scholar
  44. Spielberger, C. D. (1983). State-trait anxiety inventory manual. Redwood City, CA: Mind Garden, Inc.Google Scholar
  45. Weierich, M. R., Treat, T. A., & Hollingworth, A. (2008). Theories and measurement of visual attention processing in anxiety. Cognition and Emotion, 22(6), 985–1018.CrossRefGoogle Scholar
  46. Williams, J. M. G., Watts, F. N., MacLeod, C., & Mathews, A. (1997). Cognitive psychology and emotional disorders (2nd ed.). Chichester: Wiley.Google Scholar
  47. Wilson, E., & MacLeod, C. (2003). Contrasting two accounts of anxiety-linked attentional bias: Selective attention to varying levels of stimulus threat intensity. Journal of Abnormal Psychology, 112(2), 212–218.  https://doi.org/10.1037/0021-843X.112.2.212.CrossRefPubMedGoogle Scholar
  48. Yiend, J., & Mathews, A. (2001). Anxiety and attention to threatening pictures. The Quarterly Journal of Experimental Psychology A: Human Experimental Psychology, 54A(3), 665–681.  https://doi.org/10.1080/02724980042000462.CrossRefGoogle Scholar
  49. Zvielli, A., Bernstein, A., & Koster, E. H. W. (2014a). Dynamics of attentional bias to threat in anxious adults: Bias towards and/or away? PLoS ONE, 9(8), 1–8.  https://doi.org/10.1371/journal.pone.0104025.CrossRefGoogle Scholar
  50. Zvielli, A., Bernstein, A., & Koster, E. H. W. (2014b). Temporal dynamics of attentional bias. Clinical Psychological Science.  https://doi.org/10.1177/2167702614551572.Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.St. Francis CollegeBrooklynUSA
  2. 2.Department of Psychology, Hunter CollegeThe City University of New YorkNew YorkUSA
  3. 3.The Graduate School and University CenterThe City University of New YorkNew YorkUSA

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