Measurement Techniques

, Volume 61, Issue 8, pp 836–839 | Cite as

Estimate of Nonuniformity of Dose Distribution in Regime of Total Therapeutic Irradiation with In Vivo Dosimetry Using Semiconductor Detectors

  • I. M. LebedenkoEmail author
  • S. S. Khromov
  • D. V. Neudakhin
  • A. A. Belova

We have estimated the nonuniformity of the dose distribution along the body of a patient using in vivo dosimetry by semiconductor detectors with total therapeutic irradiation of cancer patients before bone marrow transplantation. The method of in vivo dosimetry was developed and used at the Blokhin Oncology Center since 2007. Based on the results of the investigation of 35 patients, we determined a mean nonuniformity of 10–15% of the dose distribution along the body of the patient, which conforms to international recommendations. We show a linear dependence of the accumulated dose on the mass of the patient.


in vivo dosimetry semiconductor detectors radiation therapy total irradiation 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • I. M. Lebedenko
    • 1
    • 2
    Email author
  • S. S. Khromov
    • 1
  • D. V. Neudakhin
    • 1
  • A. A. Belova
    • 1
  1. 1.Blokhin National Medical Research Center of OncologyMinistry of Health of the Russian FederationMoscowRussia
  2. 2.National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)MoscowRussia

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