Molecular Biology

, Volume 39, Issue 4, pp 482–494 | Cite as

Specific Features of Metabolism and Functions of High-Molecular Inorganic Polyphosphates in Yeasts as Representatives of Lower Eukaryotes

  • I. S. Kulaev
  • V. M. Vagabov
  • T. V. Kulakovskaya
  • N. A. Andreeva
  • L. P. Lichko
  • L. V. Trilisenko
Review and Experimantal Articles


This review considers recent data demonstrating an important role of high-molecular-weight inorganic polyphosphates (polyPs) in regulatory processes in yeasts. PolyPs occur in various compartments of the cell and are metabolized by compartment-specific sets of enzymes. Evidence is provided for the multiplicity of polyP functions in the cells. Data on the pleiotropic effects of mutations of genes coding for polyP-metabolizing enzymes are summarized.

Key words

inorganic polyphosphate exopolyphosphatase endopolyphosphatase metabolism yeast 


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Copyright information

© MAIK “Nauka/Interperiodica” 2005

Authors and Affiliations

  • I. S. Kulaev
    • 1
    • 2
  • V. M. Vagabov
    • 2
  • T. V. Kulakovskaya
    • 2
  • N. A. Andreeva
    • 2
  • L. P. Lichko
    • 2
  • L. V. Trilisenko
    • 2
  1. 1.Biological FacultyMoscow State UniversityMoscowRussia
  2. 2.Skryabin Institute of Biochemistry and Physiology of MicroorganismsRussian Academy of SciencesPushchino, Moscow RegionRussia

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