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Maternal and Child Health Journal

, Volume 20, Issue 6, pp 1296–1304 | Cite as

Association Between Low Dairy Intake During Pregnancy and Risk of Small-for-Gestational-Age Infants

  • Rocío Olmedo-Requena
  • Carmen Amezcua-Prieto
  • Juan de Dios Luna-Del-Castillo
  • Anne-Mary Lewis-Mikhael
  • Juan Mozas-Moreno
  • Aurora Bueno-Cavanillas
  • José Juan Jiménez-Moleón
Article

Abstract

Background Inadequate maternal nutrition is regarded as one of the most important indicators of fetal growth. The aim of this study was to analyze the associated risk of having a small for gestational age (SGA) infant according to the mother’s dairy intake during the first half of pregnancy. Methods A prospective cohort study was performed using 1175 healthy pregnant women selected from the catchment area of Virgen de las Nieves University Hospital, Granada (Spain). SGA was defined as neonates weighing less than the 10th percentile, adjusted for gestational age. Factors associated with SGA were analyzed using logistic regression models. Population attributable fractions of SGA according to dairy intake were estimated. Results Dairy intake among women who gave birth to SGA infants was 513.9, versus 590.3 g/day for women with appropriate size for gestational age infants (P = 0.003). An increased intake of dairy products by 100 g/day during the first half of pregnancy decreased the risk of having a SGA infant by 11.0 %, aOR = 0.89 (0.83, 0.96). A dose–response gradient between dairy intake and SGA was observed. Conclusions An inadequate intake of dairy products is associated with a higher risk of SGA. Our results suggest a possible causal relation between dairy intake during pregnancy and the weight of the newborn, although we cannot discard residual confounding. These results should be further supported by properly designed studies.

Keywords

Maternal nutrition Dairy intake Pregnancy Population attributable fraction Small for gestational age 

Abbreviations

SGA

Small for gestational age

LGA

Large for gestational age

AGA

Appropriate size for gestational age

MET

Metabolic equivalent of task

aOR

Adjusted odds ratio

PAF

Population attributable fraction

DAG

Directed acyclic graph

Notes

Acknowledgments

The authors thank Jean Sanders for improving the use of English in the manuscript. The results of this study are part of Ph.D. work of Rocío Olmedo-Requena. The present study was funded by FIS Scientific Research Project PI 03/1207 and Junta de Andalucía Excellence Project 2005 CTS 942, as well as the Biomedical Research Centre Network for Epidemiology and Public Health (CIBERESP).

Compliance with Ethical Standards

Conflict of interest

The authors of this paper declare that they have no conflicts of interest.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Rocío Olmedo-Requena
    • 1
    • 2
    • 3
  • Carmen Amezcua-Prieto
    • 1
    • 2
    • 3
  • Juan de Dios Luna-Del-Castillo
    • 2
    • 4
  • Anne-Mary Lewis-Mikhael
    • 1
  • Juan Mozas-Moreno
    • 3
    • 5
  • Aurora Bueno-Cavanillas
    • 1
    • 2
    • 3
  • José Juan Jiménez-Moleón
    • 1
    • 2
    • 3
  1. 1.Department of Preventive Medicine and Public HealthUniversity of GranadaGranadaSpain
  2. 2.Instituto de Investigación Biosanitaria ibs.GRANADAComplejo Hospitales Universitarios de Granada/Universidad de GranadaGranadaSpain
  3. 3.CIBER Epidemiología y Salud Pública (CIBERESP)MadridSpain
  4. 4.Department of Statistics and Operative InvestigationUniversity of GranadaGranadaSpain
  5. 5.Obstetrics and Gynecology ServiceVirgen de las Nieves University HospitalGranadaSpain

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