Maternal and Child Health Journal

, Volume 18, Issue 5, pp 1205–1214

Maternal Influenza Vaccination: Evaluation of a Patient-Centered Pamphlet Designed to Increase Uptake in Pregnancy

  • Pamela M. Meharry
  • Regina M. Cusson
  • Robert Stiller
  • Marietta Vázquez


We developed and tested a theoretically-based pamphlet entitled ‘Influenza in Pregnancy,’ specifically designed to increase pregnant women’s knowledge, reduce barriers to maternal vaccination, and subsequently improve vaccine uptake. A randomized control trial was conducted on pregnant women (n = 135) at three locations in Connecticut during the 2011–2012 season to evaluate the impact of the patient-centered pamphlet. The women were randomized to one of three groups: the pamphlet; pamphlet/benefit statement (vaccinating the pregnant woman also benefits the young infant); or control. A Chi square analysis compared the intervention with control using the primary outcome of vaccination. A secondary outcome of the perceptions of health beliefs of maternal vaccination were measured through General Linear Model/ANOVA model for repeated measures. Overall 66.9 % (89/133) were vaccinated. Both the pamphlet group 72.9 % (35/48) (χ² = 6.81, df = 1 p = .009), and the pamphlet/benefit statement group 86.1 % (31/36) (χ² = 13.74, df = 1, p < .001), had significantly higher vaccine uptake than the control group 46.9 % (23/49). The potential barrier, perception of vaccine safety (F = 4.973, df = 2, p < .01), and benefit of vaccination to mother and infant (F = 6.690, df = 2, p < .01) significantly improved for the intervention groups compared to control group. The pamphlet significantly increased the pregnant women’s perceptions of the safety and benefit of the vaccine, and the overall uptake.


Pregnancy Influenza Vaccination Pamphlet Newborn 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Pamela M. Meharry
    • 1
  • Regina M. Cusson
    • 2
  • Robert Stiller
    • 3
  • Marietta Vázquez
    • 4
  1. 1.Department of PediatricsMiddlesex HospitalMiddletownUSA
  2. 2.School of NursingUniversity of ConnecticutStorrsUSA
  3. 3.Department of Maternal Fetal Medicine, Bridgeport HospitalBridgeportUSA
  4. 4.Department of Pediatrics, Yale University School of MedicineNew HavenUSA

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