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Novel Predicted B-Cell Epitopes of PSMA for Development of Prostate Cancer Vaccine

  • Pejman Hashemzadeh
  • Vajihe Ghorbanzadeh
  • Seyede Maryam Valizadeh Otaghsara
  • Hassan DariushnejadEmail author
Article
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Abstract

Prostate cancer is one of the most common cancers around the world. Vaccines are a new hope for prevention of this cancer. In the case of prostate cancer, PSMA is considered as a target for vaccine development. Here, the initial data from the computational analysis of this specific antigen of the prostate membrane to find potential B-cell epitopes are described using a new bioinformatic tools. Based on the results, 673RHVIYAPSSHNKYAGE25 is the peptide with best binding affinity. These data may be useful for the effective vaccines development.

Keywords

Prostate cancer B-cell Epitope PSMA 

Notes

Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of Medical Biotechnology, Faculty of MedicineLorestan University of Medical SciencesKhorramabadIran
  2. 2.Razi Herbal Medicines Research CenterLorestan University of Medical SciencesKhorramabadIran

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