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Journal of Thermal Analysis and Calorimetry

, Volume 137, Issue 6, pp 2135–2146 | Cite as

Development of temperature stabilization system for biological sample’s microscope

  • Michal FrivaldskyEmail author
  • Miroslav Pavelek
Article
  • 21 Downloads

Abstract

This paper deals with the development proposal of a heating system for maintaining a required temperature of a microscopic biological sample, which are located within the detection area of the microscope. The need for maintaining a specific temperature of a biological sample is given by the viability of the microorganism what is related to the temperature of their internal medium. Meeting the conditions for changing or maintaining the required temperature is especially necessary in cases such as monitoring the growth of microorganisms and within the temperature-dependent mutations. In this paper, several alternatives are presented, while the best possible design of the heating element is investigated through thermal simulation analysis. Consequently, the proposal for an appropriate control algorithm for the selected heating system and its arrangement is given together with its verification within the experimental sample of the microscope.

Keywords

Joule heating A biological sample Microscope Thermal simulations Thermal regulation 

Notes

Acknowledgements

The authors wish to thank Slovak grant agency VEGA for Project No. 1/0547/18—research for the system optimization of the wireless power transfer systems. Experimental verifications and simulation experiments were performed with the help of financial support to R&D operational program centre of excellence of power electronics systems and materials for their components Nos. OPVaV-2008/2.1/01-SORO, ITMS 26220120003, and ITMS 26220120046 funded by European regional development fund (ERDF).

References

  1. 1.
    Pepper I, Gerba Ch, Gentry T. Enviromental microbiology. 3rd ed. Amsterdam: Elsevier; 2013.Google Scholar
  2. 2.
    Griffiths A, Miller J, Suzuki D. An introduction to genetic analysis. 7th ed. New York: W.H. Freeman; 2000.Google Scholar
  3. 3.
    Fasihi Z, Zakeri-Milani P, Nokhodchi A, et al. Thermodynamic approaches for the prediction of oral drug absorption. J Therm Anal Calorim. 2017;130:1371.  https://doi.org/10.1007/s10973-017-6473-3.CrossRefGoogle Scholar
  4. 4.
    Guihong TM, Christopher F, Change T. Temperature-sensitive mutations made easy: generating conditional mutations by using temperature-sensitive inteins that function within different temperature. Genetics. 2009;183:13–22.CrossRefGoogle Scholar
  5. 5.
    Koniar D, Hargas L, Stofan S. High speed video system for tissue measurement based on PWM regulated dimming and virtual instrumentation. Elektron Elektrotech. 2010;10:169–72.Google Scholar
  6. 6.
    Kuo-Chi L. Thermal propagation analysis for living tissue with surface heating. Int J Therm Sci. 2008;47(5):507–13.CrossRefGoogle Scholar
  7. 7.
    Verma RKJ, Calorim Therm Anal. Challenges in education in thermal analysis and calorimetry. J Therm Anal Calorim. 2013;113:1675.  https://doi.org/10.1007/s10973-013-3135-y.CrossRefGoogle Scholar
  8. 8.
    Agrawal M, Pardasani KR, Adlakha N. Finite element model to study the thermal effect of tumors in dermal regions of irregular tapered shaped human limbs. Int J Therm Sci. 2015;98:287–95.CrossRefGoogle Scholar
  9. 9.
    Su CH, Wu SH, Shen SJ, et al. Thermal characteristics and regeneration analyses of adsorbents by differential scanning calorimetry and scanning electron microscope. J Therm Anal Calorim. 2009;96:765.  https://doi.org/10.1007/s10973-009-0024-5.CrossRefGoogle Scholar
  10. 10.
    Kéri O, Bárdos P, Boyadjiev S, et al. Thermal properties of electrospun polyvinylpyrrolidone/titanium tetraisopropoxide composite nanofibers. J Therm Anal Calorim. 2019.  https://doi.org/10.1007/s10973-019-08030-0.Google Scholar
  11. 11.
    Hargas L, Koniar D, Hrianka M. Adjusting and conditioning of high speed videosequences for diagnostic purposes in medicine. In: 10th international conference ELEKTRO 2014; 2014. p. 548–52.Google Scholar
  12. 12.
    Nomoto T, Imajo S, Yamashita S, et al. Construction of a thermal conductivity measurement system for small single crystals of organic conductors. J Therm Anal Calorim. 2018.  https://doi.org/10.1007/s10973-018-7799-1.Google Scholar
  13. 13.
    Ge MY, Shu C, Chua KJ, Yang WM. Numerical analysis of a clinically-extracted vascular tissue during cryo-freezing using immersed boundary method. Int J Therm Sci. 2016;110:109–18.CrossRefGoogle Scholar
  14. 14.
    Chen M, Dongxu O, Cao S, et al. Effects of heat treatment and SOC on fire behaviors of lithium-ion batteries pack. J Therm Anal Calorim. 2018.  https://doi.org/10.1007/s10973-018-7864-9.Google Scholar
  15. 15.
    Koniar D, Hargas L, Loncova Z. Visual system-based object tracking using image segmentation for biomedical applications. Electr Eng. 2017;99(4):1349–66.CrossRefGoogle Scholar
  16. 16.
    Zhu J, Fu S, Li K, et al. Thermal stability assessment of a new energetic Ca(II) compound with ZTO ligand by DSC and ARC. J Therm Anal Calorim. 2018;134:1873.  https://doi.org/10.1007/s10973-018-7552-9.CrossRefGoogle Scholar
  17. 17.
    Mashayekhi R, Khodabandeh E, Akbari OA, et al. CFD analysis of thermal and hydrodynamic characteristics of hybrid nanofluid in a new designed sinusoidal double-layered microchannel heat sink. J Therm Anal Calorim. 2018;134:2305.  https://doi.org/10.1007/s10973-018-7671-3.CrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2019

Authors and Affiliations

  1. 1.Department of Mechatronics and Electronics, Faculty of Electrical EngineeringUniversity of ZilinaŽilinaSlovakia

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