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Journal of Thermal Analysis and Calorimetry

, Volume 134, Issue 3, pp 1965–1973 | Cite as

Thermal, spectroscopic and in vitro antimicrobial analysis of 2, 2′-(2-((carboxymethyl)(2-(2-hydroxyethoxy)-2-oxoethyl)amino)ethylazanediyl)diacetatocobalt(II)/manganese(II) hydrate

  • A. Jeya RajendranEmail author
  • Soven Dhawa
  • G. Jeya Jothi
  • A. Hannah Hepsibah
Article
  • 43 Downloads

Abstract

Co(II), and Mn(II) complexes using 2,2′-(2-((carboxymethyl)(2-(2-hydroxyethoxy)-2-oxoethyl)amino)ethylazanediyl)diacetato (SCHOEA), derivative of disodium salt of EDTA were synthesized by three stages and characterized by spectroscopic (UV–Visible, FTIR, EPR, 1H NMR) techniques, magnetic susceptibility measurements and thermal studies (TA). Electronic and magnetic susceptibility measurements indicated low-spin octahedral complexes. The FTIR spectra supported the coordination mode of the ligand as hexadentate with the metal ions. Molar conductivity supported the non-electrolytic nature of the complexes. The EPR spectra confirmed the distorted octahedral geometry of the complexes based on the computation of Hamiltonian parameters and the degree of covalency. In vitro antimicrobial activities of the ligand and metal complexes against three bacterial (Enterobacteraerogenes, Micrococcus luteus, Shigellaflexineria) and two fungal species (Candida albicans, Aspergillusflavus) were performed by disc diffusion method which revealed that the complexes are more potent bactericides and fungicides than the ligand.

Keywords

Hexadentate ligand Derivative of EDTA Cobalt(II)/manganese(II) complex Thermal studies Hamiltonian parameters In vitro antimicrobial activity 

Notes

Funding

The funding was provided by LCTOI Project (Grant No. 2LCTOI14CHM002).

Supplementary material

10973_2018_7729_MOESM1_ESM.docx (857 kb)
Supplementary material 1 (DOCX 857 kb)

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Copyright information

© Akadémiai Kiadó, Budapest, Hungary 2018

Authors and Affiliations

  • A. Jeya Rajendran
    • 1
    Email author
  • Soven Dhawa
    • 1
  • G. Jeya Jothi
    • 2
  • A. Hannah Hepsibah
    • 2
  1. 1.Advanced Materials Research Laboratory, Department of ChemistryLoyola CollegeChennai, 600034India
  2. 2.Department of Plant Biology and BiotechnologyLoyola CollegeChennaiIndia

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