Synthesis and polymorphism evaluation of the 3,5-bis(decyloxy)benzaldehyde
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In this work, 3,5-bis(decyloxy)benzaldehyde, a precursor of long chain amphiphilic BODIPYs, was synthesized and its polymorphic behavior was characterized by differential scanning calorimetry, polarized light thermo microscopy, infrared spectroscopy, and XRPD. From the combined use of these techniques, an interesting polymorphic behavior was observed, and four polymorphs were identified. The initial compound melts around room temperature, ca. 30 °C, and several polymorphic forms of lower melting point are obtained by cooling the melt. A thermal program could be developed that allows obtaining each form independently.
Keywords3,5-bis(decyloxy)benzaldehyde Polymorphism Calorimetry Thermomicroscopy
This work was supported by PEst-C/QUI/UI0313/2011, PEst-OE/SAU/UI0177/2011 FCT (FEDER), PEst-C/FIS/UI0036/2011, and FCT/QREN-COMPETE through projects PTDC/AAC-CLI/098308/2008, PTDC/AAC-CLI/118092/2010, and SFRH/BD/48269/2008.
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