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The physicochemical and biological properties of zinc(II) complexes

  • Erika Szunyogová
  • Dagmar Mudroňová
  • Katarína GyöryováEmail author
  • Radomíra Nemcová
  • Jana Kovářová
  • Lenka Piknová-Findoráková
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Abstract

Spectroscopic (IR), thermoanalytical (TG/DTG, DTA) and biological methods were applied to investigate physicochemical and biological properties of seven zinc(II) complex compounds of the following formula Zn(HCOO)2·2H2O (I), Zn(HCOO)2·tph (II), Zn(CH3COO)2·2H2O (III), Zn(CH3COO)2·tph (IV), Zn(CH3COO)2·2phen (V), Zn(CH3CH2COO)2·2H2O (VI), Zn(CH3CH2CH2COO)2·2H2O (VII), where tph=theophylline, phen=phenazone. The formation of various intermediates during thermal decomposition suggests the dependence on the length of aliphatic carboxylic chain and type of N-donor ligand (tph, phen). The final product of the thermal decomposition was ZnO. The antimicrobial activity of these complexes were tested against G+ and G bacteria. Strong inhibitive effect was observed towards E. coli, salmonellae and Staph. aureus.

Keywords

antimicrobial activity complexes IR spectra thermal properties Zn(II) 

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References

  1. 1.
    Stefanitsi, D, Garel, JR 1997Lett. Appl. Microbiol.24180PubMedCrossRefGoogle Scholar
  2. 2.
    Coleman, JE 1992Ann. Rev. Biophys. Biomol. Struct.21441CrossRefGoogle Scholar
  3. 3.
    Fridovich, I 1978Science201875PubMedCrossRefADSGoogle Scholar
  4. 4.
    Beveridge, TJ, Doyle, RJ,  et al. 1989Metal Ions and BacteriaWileyNew YorkGoogle Scholar
  5. 5.
    Holm, A, Poulsen, HD 1996Compend. Cont. Educ. Prac. Vet.1826Google Scholar
  6. 6.
    Győryová, K, Kovářová, J, Chomič, J 2005J. Therm. Anal. Cal.80375CrossRefGoogle Scholar
  7. 7.
    Győryová , K, Chomič, J, Szunyogová, E, Piknová, L, Zeleňák, V, Vargová, Z 2006J. Therm. Anal. Cal.84727CrossRefGoogle Scholar
  8. 8.
    Vargová, Z, Zeleňák, V, Císařová, I, Győryová, K 2004Thermochim. Acta423149CrossRefGoogle Scholar
  9. 9.
    Král’ová, K, Masarovičová, E, Győryová, K 2003Fresenius Environ. Bull.12857Google Scholar
  10. 10.
    Bellamy, M,  et al. 1954The Infra-Red Spectra of Complex MoleculesWileyNew YorkGoogle Scholar
  11. 11.
    Nakamoto, K,  et al. 1986Infrared and Raman Spectra of Inorganic CompoundsJohn WileyNew YorkGoogle Scholar
  12. 12.
    Melník, M, Anderová, M, Hol’ko, M 1982Inorg. Chim. Acta67117CrossRefGoogle Scholar
  13. 13.
    Dreosti, IE 1996Nutr. Rev.54S51PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Erika Szunyogová
    • 1
  • Dagmar Mudroňová
    • 2
  • Katarína Györyová
    • 3
    Email author
  • Radomíra Nemcová
    • 2
  • Jana Kovářová
    • 4
  • Lenka Piknová-Findoráková
    • 3
  1. 1.Department of BiophysicsSlovak Academy of ScienceKošiceSlovak Republic
  2. 2.Research Institute of Gnotobiology and Prevention of Diseases in YoungUniversity of Veterinary MedicineKošiceSlovak Republic
  3. 3.Department of Inorganic ChemistryP. J. Šafarik UniversityKošiceSlovak Republic
  4. 4.Institute of Macromolecular Chemistry AV ČRPraha 6Czech Republic

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