Original Paper: Sol-gel and hybrid materials for biological and health (medical) applications
Pure and Ag-doped zinc oxide sol–gel thin films were prepared by spin-coating process. Pure and Ag–ZnO films, containing 2–8% Ag, were annealed at 500 °C for 2 h. All thin films were prepared and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM), and UV–visible spectroscopy. X-ray diffraction studies show the polycrystalline nature with hexagonal wurtzite structure of ZnO and Ag:ZnO thin films. The crystallite size of the prepared samples reduced with increasing Ag doping concentrations. AFM and SEM results indicated that the average crystallite size decreased as Ag doping concentration increased. The transmittance spectra were then recorded at wavelengths ranging from 300 to 1000 nm. The films produced yielded high transmission at visible regions. The optical band gap energy of spin-coated films also decreased as Ag doping concentration increased. In particular, their optical band gap energies were 3.75, 3.55, 3.4, 3.3, and 3.23 eV at 0%, 2%, 4%, 6%, and 8%, respectively. Antibacterial activity of pure and Ag-doped zinc oxide against Escherichia coli and Staphylococcus aureus was evaluated by international recognized test (JIS Z 2801). The results showed that pure and Ag-doped ZnO thin film has an antibacterial inhibition zone against E. coli and S. aureus. Gram-positive bacteria seemed to be more resistant to pure and Ag-doped ZnO thin film than gram-negative bacteria. The test shows incrementally increasing in antibacterial activity of the thin films when dopant ratio increased under UV light.
Pure and Ag-doped zinc oxide sol–gel thin films were prepared by spin coating process. Pure and Ag–ZnO films, containing 2–8% Ag, in comparing with other researchers, Ag was added to the ZnO thin films with high concentration.
It was found that Ag concentration was affected on surface roughness, grain size, absorption of UV light and antibacterial activity of the samples.
The antibacterial activity of pure and Ag doped ZnO thin films improved under UV light for 1 h at room temperature. The presence of the silver in zinc oxide structure enhanced the antibacterial activity up to 99.32% against S. aureus and E. coli at 6% Ag–ZnO prepared films. All prepared films have hexagonal wurtzite structure. Moreover, the antibacterial activity of thin films against S. aureus under UV light irradiation (365 nm, 8 W) has been developed in this research.
ZnO thin films Structural properties Optical properties Sol–gel spin coating Ag doping antimicrobial activity
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Conflict of interest
The authors declare that they have no conflict of interest.
Joshy NV, Johney Isaac, Jayaraj MK (2008) Characterization of ZnO plasma in a radio frequency sputtering system. J Appl Phys 103:123305CrossRefGoogle Scholar
Lu ZL, Yan GQ,Wang S, Zou WQ, Mo ZR, Lv LY, Zhang FM, Du YW, Xu MX, Xia ZH (2008) Influence of the oxidative annealing temperature on the magnetism of (Mn, N)- codoped ZnO thin films. J Appl Phys 104:033919CrossRefGoogle Scholar
Irimpan L, Ambika D, Kumar V, Nampoori VPN, Radhakrishnan P (2008) Effect of annealing on the spectral and nonlinear optical characteristics of thin films of nano- ZnO. J Appl Phys 104:033118CrossRefGoogle Scholar
Sathya M, Claude A, Govindasamy P, Sudha K (2012) Growth of pure and doped ZnO thin films for solar cell applications. Adv Appl Sci Res 3(5):2591–2598Google Scholar
Raji R, Gopchandran KG (2017) ZnO nanostructures with tunable visible luminescence: Effects of kinetics of chemical reduction and annealing. J Sci: Adv Mater Devices 2(1):51–58Google Scholar
Chen M-J, Yang J-R, Shiojiri M (2012) ZnO-based ultra-violet light emitting diodes and nanostructures fabricated by atomic layer deposition. Semicond Sci Technol 27:074005CrossRefGoogle Scholar
Ajimsha RS, Vanaja KA, Jayaraj MK, Misra P, Dixit VK, Kukreja LM (2007) Transparent p-AgCoO2/n-ZnO diode heterojunction fabricated by pulsed laser deposition. Thin Solid Films 515:7352–7356CrossRefGoogle Scholar
Lu Y, Lin Y, Wang D, Wang L, Xie T, Jiang T (2011) A high performance cobalt-doped ZnO visible light photocatalyst and its photogenerated charge transfer properties. Nano Res 4(11):1144–1152CrossRefGoogle Scholar
Song J, Zhou J, Wang ZL (2006) Piezoelectric and semiconducting coupled power generating process of a single ZnO belt/wire. A technology for harvesting electricity from the environment. Nano Lett 6:1656–1662CrossRefGoogle Scholar
Wang ZL, Annu. (2004) Functional oxide nanobelts: materials, properties and potential applications in nanosystems and biotechnology. Rev Phys Chem 55:159CrossRefGoogle Scholar
Kaneva NV, Dushkin CD (2011) Preparation of nanocrystalline thin films of ZnO by sol-gel dip coating. Bulg Chem Commun 43:259Google Scholar
Ahmad M, Zhao J, Iqbal J, Miao W, Xie L, Mo R, Zhu J (2009) Conductivity enhancement by slight indium doping in ZnO nanowires for optoelectronic applications. J Phys D Appl Phys 42(16):165406CrossRefGoogle Scholar
Lupan O, Chow L, Ono LK, Cuenya BR, Chai G, Khalla Hf, Park S, Schulte A (2010) Synthesis and Characterization of Ag- or Sb-Doped ZnO Nanorods by a Facile Hydrothermal Route. J Phys Chem C 114:12401–12408CrossRefGoogle Scholar
Mei CX, Yong J, Yong GX, Wei ZX (2012) Ag-doped ZnO nanorods synthesized by two-step method. Chin Phys B 11(21):116801Google Scholar
Jamil NY, Najim SA, Muhammed AM, Rogoz VM (2014) Preparation, structural and optical characterization of ZnO/Ag thin film by CVD. Proc Int Conf Nanomater: Appl Prop 3(2):02NEA09Google Scholar
Bose S, Ray S, Barua AK (1996) Textured aluminium-doped ZnO thin films prepared by magnetron sputtering. J Phys D Appl Phys 29:1873–1877CrossRefGoogle Scholar
Rad MS, Kompany A, Zak AK, Javidi M, Mortazavi S (2013) J Nanopart Res 15:1Google Scholar
Darroudi M, Sabouri Z, Oskuee R Kazemi, Khorsand Zak A, Kargar H, Mhna Hamid (2013) Sol-gel synthesis, characterization, and neurotoxicity effect of zinc oxide nanoparticles using gum tragacanth. Ceram Int 39:9195CrossRefGoogle Scholar
Polley TA, Carter WB, Poker DB (1999) Deposition of zinc oxide thin films by combustion CVD. Thin Solid Films 357:132–136CrossRefGoogle Scholar
Al-Salman HS, Abdullah M (2013) RF sputtering enhanced the morphology and photoluminescence of multi-oriented ZnO nanostructure produced by chemical vapor deposition. J Alloy Compd 547:132CrossRefGoogle Scholar
Shewale P, Agawane G, Shin S, Moholkar A, Lee J, Kim J, Uplane M, Sens B (2013) Thickness dependent H2S sensing properties of nanocrystalline ZnO thin films derived by advanced spray pyrolysis. Actuators Chem 177:695CrossRefGoogle Scholar
Wayu MB, Spidle RT, Devkota T, Deb AK, Delong RK, Ghosh KC, Wanekaya AK, Chusuei CC (2013) Morphology of hydrothermally synthesized ZnO nanoparticles tethered to carbon nanotubes affects electrocatalytic activity for H2O2 detection. Electrochim Acta 97:99CrossRefGoogle Scholar
Wang J-L, Hsieh T-Y, Yang P-Y, Hwang C-C, Shye D-C, Lee I-C (2013) Oxygen annealing effect on field-emission characteristics of hydrothermally synthesized Al-doped ZnO nanowires. Surf Coat Technol 231:423CrossRefGoogle Scholar
Al-Jawad SMH, Elttayf AK, Sabr AlS (2017) Influence of Annealing Temperature on the Characteristics of Nanocrystalline SnO2 Thin Films Produced by Sol–Gel and Chemical Bath Deposition for Gas Sensor Applications. Surf Rev Lett 24(7):1750104CrossRefGoogle Scholar
Al-Jawad SMH, Elttayf AK, Sabr AS (2017) Studying Structural, Optical, Electrical, and Sensing Properties of Nanocrystalline SnO2:Cu Films Prepared by Sol-Gel Method for CO Gas Sensor Application at Low Temperature. Surf Rev Lett 24(8):1750110CrossRefGoogle Scholar
AL-Jawad SMH (2017) Influence of multilayer deposition on characteristics of nanocrystalline SnO2 thin films produce by sol-gel technique for gas sensor application. Optik 146:17–26CrossRefGoogle Scholar
Al-Jawad SMH (2017) Comparative study between CBD and SILAR methods for deposited TiO2, CdS, and TiO2/CdS core-shell structure. Mater Sci Semicond Process 67:75–83CrossRefGoogle Scholar
Taha AA, AL-Jawad SMH, Salim MM (2018) Influence of titanium tetraisopropoxide concentration on the antibacterial activity of TiO2 thin films. Surf Rev Lett 1850111:8. https://doi.org/10.1142/S0218625X18501111
Kreysa G, Ota K, Savinell RF (2014) Encyclopedia of Applied Electrochemistry 343–346.Google Scholar
AL-Jawad SMH, Taha AA, Salim MM (2017) Synthesis and characterization of pure and Fe doped TiO2 thin films for antimicrobial activity. Optik 142:42–53CrossRefGoogle Scholar
Karunakaran C, Rajeswari V, Gomathisankar P (2011) Combustion synthesis of zno and ag-doped zno and their bactericidal and photocatalytic activities. Super Lattices Microstruct 50(3):234–241CrossRefGoogle Scholar
Pillai SC, Kelly JM, McCormack DE, Raghavendra RJ (2004) Self-assembled arrays of ZnO nanoparticles and their application as varistor materials. Mater Chem 14:1572CrossRefGoogle Scholar
Murtaza G, Ahmad R, Rashid M, Hassan M, Hussnain A, Khan MA, Ehsan ul Haq M, Shafique M, Riaz S (2014) Structural and magnetic studies on zr doped zno diluted magnetic semiconductor. Curr Appl Phys 14(2):176–181CrossRefGoogle Scholar
Salaken SM, Farzana E, Podder J (2013) Effect of Fe-doping on the structural and optical properties of ZnO thin films prepared by spray pyrolysis. J Semicond 34:073003–1-6CrossRefGoogle Scholar
Ashikin Kamaruddin S, Yoong Chan K, Kwang YowMohd Ho, Sahdan Z, Saim H, Knipp D (2011) Zinc oxide films prepared by sol–gel spin coating technique. Appl Phys A 104:263–268Google Scholar
AL-Jawad SMH, Mohammad MR, Jamal IN (2018) Effect of Electrolyte Solution on Structural and Otical Properties of TiO2 Grown by Anodization Techniqye for Photoelectrocatalytic Application. Surf Rev Lett 25(5):16 https://doi.org/10.1142/S0218625X18500786.
AL-Jawad SMH, Salman O, Yousif NA (2018) Influence of growth time on structural, optical and electrical properties of TiO2 nanorod arrays deposited by hydrothermal method. Surf Rev Lett 1850155 (9 pages), https://doi.org/10.1142/S0218625X1850155X.
Gupta MK, Sinha N, Kumar B (2011) p-type k-doped ZnO nanorods for optoelectronic applications. J Appl Phys 109:8Google Scholar
Xiaolu Y, Dan H, Hangshi L, Linxiao L, Xiaoyu C, Yude W (2011) Nanostructure and optical properties of M doped ZnO (M=Ni, Mn) thin films prepared by sol–gel process. Phys B: Condens Matter 406:3956CrossRefGoogle Scholar
Jeong SH, Park BN, Lee SB, Boo J-H (2005) Structural and optical properties of silver-doped zinc oxide sputtered films. Surf Coat Technol 193:340–344CrossRefGoogle Scholar
Brayner R, Ferrari-Iliou R, Brivois N, Djediat S, Benedetti M F, Fievet F (2006) Toxicological impact studies based on escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett 6:866CrossRefGoogle Scholar
Stoimenov PK, Klinger RL, Marchin GL, Klabunde KJ (2002) Metal oxide nanoparticles as bactericidal agents. Langmuir 18:6679CrossRefGoogle Scholar
Atmaca S, Gul K, Cicek R (1998) The effect of zinc on microbial growth. Tr J Med Sci 28:595–597Google Scholar
Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO (2000) A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res 52:662–668CrossRefGoogle Scholar
Jung WK, Koo HC, Kim KW, Shin S, Kim SH, Par YHK (2008) Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Am Soc Microbiol 74:2171Google Scholar